Title: Hotels in El Santuario - Best El Santuario Hotels from £14 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in El Santuario](https://expedia.co.uk/El-Santuario-Holiday-Rentals.d553248635943694289.Travel-Guide-HolidayRentals)[El Santuario Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-El-Santuario.d553248635943694289.Car-Hire-Guide)[El Santuario Holidays](https://expedia.co.uk/El-Santuario.d553248635943694289.Holidays-City-Breaks) ![El Santuario, Antioquia, Colombia. June 28, 2025. Panoramic drone view of the town's main church.](https://images.trvl-media.com/place/553248635943694289/ad22c12c-1309-48b4-89f4-e7d9c5e76429.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635943694289/ad22c12c-1309-48b4-89f4-e7d9c5e76429.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in El Santuario Spa [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=APARTMENT) Farm [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=AGRITOURISM) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=CABIN) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&travelerType=family_friendly) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=CONDO) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=HOT_TUB) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=COTTAGE) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=El+Santuario%2C+Antioquia%2C+Colombia®ionId=553248635943694289&latLong=6.123279%2C-75.265174&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=VILLA) ## Check prices for these dates Tonight [31 Mar - 1 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635943694289&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Apr - 2 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635943694289&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635943694289&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635943694289&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for El Santuario hotels ![Deluxe Suite, Balcony, Lake View | 1 bedroom](https://images.trvl-media.com/lodging/112000000/111650000/111646300/111646265/98b809fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony, Lake View | 1 bedroom](https://images.trvl-media.com/lodging/112000000/111650000/111646300/111646265/60ba61f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony, Lake View | 1 bedroom](https://images.trvl-media.com/lodging/112000000/111650000/111646300/111646265/203118d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony, Lake View | 1 bedroom](https://images.trvl-media.com/lodging/112000000/111650000/111646300/111646265/1a40c938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MONTANA ECO HOTEL [](https://www.expedia.co.uk/El-Santuario-Hotels-MONTANA-ECO-HOTEL.h111646265.Hotel-Information) El Santuario £105 additional charges may apply 8 Apr - 9 Apr [](https://www.expedia.co.uk/El-Santuario-Hotels-MONTANA-ECO-HOTEL.h111646265.Hotel-Information) ![Exclusive Cabin | View from room](https://images.trvl-media.com/lodging/101000000/100580000/100573500/100573456/801ef038.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100580000/100573500/100573456/7a8b227e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Cabin, 1 Queen Bed, Bathtub, Mountain View | Premium bedding, minibar, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100580000/100573500/100573456/6bb54485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Cabin | Premium bedding, minibar, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100580000/100573500/100573456/7c019ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BubbleSky Glamping Guatapé [](https://www.expedia.co.uk/Guatape-Hotels-BubbleSky-Glamping-Guatape.h100573456.Hotel-Information) Guatapé 9.0/10 Wonderful (91 reviews) "Excellent experience! Delicious breakfast and a very friendly staff! The internet connection wasn't stable but the experience made up for that. All the greenery around was amazinggggg! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yrzah £73 additional charges may apply 5 Apr - 6 Apr [](https://www.expedia.co.uk/Guatape-Hotels-BubbleSky-Glamping-Guatape.h100573456.Hotel-Information) ![Club Cabin, Accessible | Premium bedding, individually furnished, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/42000000/41060000/41051700/41051643/7cf4a606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Premium bedding, individually furnished, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/42000000/41060000/41051700/41051643/01a7d87a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot stone massages, Thai massages](https://images.trvl-media.com/lodging/42000000/41060000/41051700/41051643/c54f4602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41060000/41051700/41051643/d9747037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isak Hotel & Golf Airport [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Isak.h41051643.Hotel-Information) Rionegro 9.2/10 Wonderful (646 reviews) "Excellent accommodations and friendly staff who were helpful ensuring we arrived to the airport smoothly for our early flight. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc £56 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Isak.h41051643.Hotel-Information) ![Superior Double Room, 1 Queen Bed | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/32000000/31680000/31679100/31679095/0c2e8f34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/32000000/31680000/31679100/31679095/9c0b6600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/32000000/31680000/31679100/31679095/805d78ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31680000/31679100/31679095/7650d524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Lagoon [](https://www.expedia.co.uk/Rionegro-Hotels-Hotel-Lagoon.h31679095.Hotel-Information) Rionegro 9.2/10 Wonderful (326 reviews) "Delicious food, attentive staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARIA £83 additional charges may apply 11 Apr - 12 Apr [](https://www.expedia.co.uk/Rionegro-Hotels-Hotel-Lagoon.h31679095.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/120000000/119360000/119353300/119353229/0c8cc811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119360000/119353300/119353229/0505e97a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Balcony, Lake View | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119360000/119353300/119353229/00e994a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119360000/119353300/119353229/903404b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MYLOS Hotel Boutique [](https://www.expedia.co.uk/Guatape-Hotels-MYLOS-Hotel-Boutique.h119353229.Hotel-Information) Guatapé 8.0/10 Very good (15 reviews) "Mylos hotel was a hidden gem in Guatape. Such a cute luxury boutique hotel and near everything. From the moment we stepped in we were greeted by the wonderful staff. Hotel look just like the pictures. Will definitely stay here again in the future. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeannette £155 additional charges may apply 5 Apr - 6 Apr [](https://www.expedia.co.uk/Guatape-Hotels-MYLOS-Hotel-Boutique.h119353229.Hotel-Information) ![Minibar, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/113000000/112320000/112310200/112310194/ccf6c9d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/113000000/112320000/112310200/112310194/198ac028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/113000000/112320000/112310200/112310194/04c770b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony, Lake View | Minibar, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/113000000/112320000/112310200/112310194/3d5e6efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EL NIDO HOTEL GUATAPE [](https://www.expedia.co.uk/Guatape-Hotels-EL-NIDO-HOTEL-GUATAPE.h112310194.Hotel-Information) Guatapé 10/10 Exceptional (35 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos £116 additional charges may apply 20 Apr - 21 Apr [](https://www.expedia.co.uk/Guatape-Hotels-EL-NIDO-HOTEL-GUATAPE.h112310194.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42300000/42299200/42299153/a88c6d82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Quadruple Room, Multiple Beds, Balcony | Premium bedding, down duvets, free WiFi, bed sheets](https://images.trvl-media.com/lodging/43000000/42300000/42299200/42299153/4be87c2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room | Terrace/patio](https://images.trvl-media.com/lodging/43000000/42300000/42299200/42299153/22de18c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/43000000/42300000/42299200/42299153/a689a554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Verony Guatape [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Verony-Guatape.h42299153.Hotel-Information) Guatapé 8.2/10 Very good (121 reviews) "Parking was easy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) victoriano moises £39 additional charges may apply 15 Apr - 16 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Verony-Guatape.h42299153.Hotel-Information) ![Suite (Imperial Panoramica) | View from room](https://images.trvl-media.com/lodging/12000000/11470000/11460500/11460462/d3f1a4f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/12000000/11470000/11460500/11460462/4f8f46ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Imperial Panoramica) | Minibar, free WiFi](https://images.trvl-media.com/lodging/12000000/11470000/11460500/11460462/2b85119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Imperial Panoramica) | Jetted bathtub](https://images.trvl-media.com/lodging/12000000/11470000/11460500/11460462/9d1e4cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Los Recuerdos [](https://www.expedia.co.uk/Guatape-Hotels-Hotel-Los-Recuerdos.h11460462.Hotel-Information) Guatapé 8.2/10 Very good (619 reviews) "Stayed at Los Recuerdos for a family vacation and everyone of us loved it. Would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivert £65 additional charges may apply 26 Apr - 27 Apr [](https://www.expedia.co.uk/Guatape-Hotels-Hotel-Los-Recuerdos.h11460462.Hotel-Information) ![Deluxe Room | Living area](https://images.trvl-media.com/lodging/93000000/92340000/92337600/92337579/b52d664a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room | Private kitchen | Coffee/tea maker, electric kettle, cookware/dishes/utensils](https://images.trvl-media.com/lodging/93000000/92340000/92337600/92337579/af0bf4dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker, electric kettle, cookware/dishes/utensils](https://images.trvl-media.com/lodging/93000000/92340000/92337600/92337579/22992ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/93000000/92340000/92337600/92337579/878d84ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porto Marina Hotel [](https://www.expedia.co.uk/El-Penol-Hotels-Porto-Marina-Hotel.h92337579.Hotel-Information) El Peñol 9.2/10 Wonderful (113 reviews) "It’s a beautiful intimate escape!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cam £58 additional charges may apply 7 Apr - 8 Apr [](https://www.expedia.co.uk/El-Penol-Hotels-Porto-Marina-Hotel.h92337579.Hotel-Information) ![Deluxe Apartment | In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/49000000/48540000/48540000/48539935/ca8a9198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/49000000/48540000/48540000/48539935/0dfde9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/49000000/48540000/48540000/48539935/f8f4093b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48540000/48540000/48539935/e7afc4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santorini [](https://www.expedia.co.uk/Guarne-Hotels-Hotel-Santorini.h48539935.Hotel-Information) Guatapé 8.4/10 Very good (83 reviews) "The room was as advertised, location is amazing, staff was kind and curtious and the only issue I had was with the WiFi. It was perfect in every other way." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lizbeth £49 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Guarne-Hotels-Hotel-Santorini.h48539935.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/97000000/96520000/96516500/96516442/69f093f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96520000/96516500/96516442/25672c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/97000000/96520000/96516500/96516442/578f111e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/97000000/96520000/96516500/96516442/dbeb17e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown, Guatape, Autograph Collection [](https://www.expedia.co.uk/Medellin-Hotels-Luxe-By-The-Charlee.h96516442.Hotel-Information) Guatapé 9.2/10 Wonderful (457 reviews) "Great resort, amazing staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hasay £202 additional charges may apply 8 Apr - 9 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Luxe-By-The-Charlee.h96516442.Hotel-Information) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/20000000/19650000/19647700/19647662/w4000h2250x0y0-7c047b14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/20000000/19650000/19647700/19647662/e3f3e534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19650000/19647700/19647662/45edefc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/20000000/19650000/19647700/19647662/44c4503a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santiago de Arma [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Santiago-De-Arma.h19647662.Hotel-Information) Rionegro 9.2/10 Wonderful (946 reviews) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario £96 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Hotel-Santiago-De-Arma.h19647662.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/108000000/107130000/107126600/107126596/2d54dcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107130000/107126600/107126596/14bc5c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/108000000/107130000/107126600/107126596/7c68ef77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107130000/107126600/107126596/53cad167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Autenthico Sajonia Hotel Aeropuerto [](https://www.expedia.co.uk/Medellin-Hotels-Autenthico-Llanogrande-Hotel-Santa-Elena.h107126596.Hotel-Information) Rionegro 9.2/10 Wonderful (75 reviews) "Staff were so wonderful very helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £37 additional charges may apply 6 Apr - 7 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Autenthico-Llanogrande-Hotel-Santa-Elena.h107126596.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/520000/519900/519824/4d45af49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/520000/519900/519824/80c91cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/520000/519900/519824/3705a3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/520000/519900/519824/649320ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Movich Hotel Las Lomas [](https://www.expedia.co.uk/Medellin-Hotels-Movich-Hotel-Las-Lomas.h519824.Hotel-Information) Rionegro 9.0/10 Wonderful (1,004 reviews) "Breakfast was really good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pilar £110 additional charges may apply 24 Apr - 25 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Movich-Hotel-Las-Lomas.h519824.Hotel-Information) ![Standard Room | Minibar, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/109000000/108900000/108899500/108899443/51fc13df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Garden View | Private kitchen](https://images.trvl-media.com/lodging/109000000/108900000/108899500/108899443/911d9332.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Garden View | View from room](https://images.trvl-media.com/lodging/109000000/108900000/108899500/108899443/25c109c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/109000000/108900000/108899500/108899443/82d64981.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Soy Local Reserva Sajonia [](https://www.expedia.co.uk/Medellin-Hotels-Soy-Local-Reserva-Sajonia.h108899443.Hotel-Information) Rionegro 8.8/10 Excellent (88 reviews) "Loved it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay £120 additional charges may apply 23 Apr - 24 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Soy-Local-Reserva-Sajonia.h108899443.Hotel-Information) ![Studio | View from room](https://images.trvl-media.com/lodging/16000000/15610000/15605400/15605397/a50308e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/16000000/15610000/15605400/15605397/f5636e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 Bedroom | Balcony view](https://images.trvl-media.com/lodging/16000000/15610000/15605400/15605397/408118d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15610000/15605400/15605397/eb29c105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelers Rio Verde Living Suites [](https://www.expedia.co.uk/Medellin-Hotels-Travelers-Rio-Verde-Living-Suites.h15605397.Hotel-Information) Rionegro 8.4/10 Very good (473 reviews) "GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £60 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Travelers-Rio-Verde-Living-Suites.h15605397.Hotel-Information) ![Indoor/outdoor pool](https://images.trvl-media.com/lodging/18000000/17520000/17514400/17514398/85dba5c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17520000/17514400/17514398/fd2b93a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17520000/17514400/17514398/0a1e3fc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/18000000/17520000/17514400/17514398/2d7821fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MG Hotels & Suites [](https://www.expedia.co.uk/Rionegro-Hotels-MG-Hotels-Suites-By-DecO.h17514398.Hotel-Information) Rionegro 8.8/10 Excellent (215 reviews) "The room was spotless, my family felt very safe. The front office staff was very accommodating, friendly and helpful with directions to the nearest mall. I would have given it 5 stars but the pool was being worked on and my granddaughters wanted to swim. Other than that, everything was well kept." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Xochitl £109 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Rionegro-Hotels-MG-Hotels-Suites-By-DecO.h17514398.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/e9dfc4b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/f74bb81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/c38800cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/0de79a6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Calle Flora Hotel by Jalo [](https://www.expedia.co.uk/Medellin-Hotels-Jalo-Calle-Flora-Hotel.h117576751.Hotel-Information) El Poblado 9.0/10 Wonderful (657 reviews) "Great place to stay, beautify. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gervacio £73 additional charges may apply 1 Apr - 2 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Jalo-Calle-Flora-Hotel.h117576751.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/71000000/70820000/70815100/70815016/298c5adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/71000000/70820000/70815100/70815016/cc9a8302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/71000000/70820000/70815100/70815016/5e2777e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas](https://images.trvl-media.com/lodging/71000000/70820000/70815100/70815016/b3acd162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marquee Hotel [](https://www.expedia.co.uk/Medellin-Hotels-Marquee-Hotel.h70815016.Hotel-Information) El Poblado 9.2/10 Wonderful (180 reviews) "Wonderful stay and the breakfast was delicious!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £114 additional charges may apply 8 Apr - 9 Apr [](https://www.expedia.co.uk/Medellin-Hotels-Marquee-Hotel.h70815016.Hotel-Information) ![In-room safe, free WiFi](https://images.trvl-media.com/lodging/124000000/123180000/123172700/123172665/8a07b324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/124000000/123180000/123172700/123172665/7843250a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/124000000/123180000/123172700/123172665/a99a83e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/124000000/123180000/123172700/123172665/f6eff5f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BoH Collection [](https://www.expedia.co.uk/Medellin-Hotels-BoH-Hotel.h123172665.Hotel-Information) El Poblado 10/10 Exceptional (2 reviews) "La habitación con jacuzzi es una belleza, las instalaciones limpias y ordenadas, la atención fue espectacular, disfrute mis vacaciones en el lugar, sin funda volvería a reservar! " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Gladis Dorian £60 additional charges may apply 20 Apr - 21 Apr [](https://www.expedia.co.uk/Medellin-Hotels-BoH-Hotel.h123172665.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-14&endDate=2026-04-15®ionId=553248635943694289&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEl-Santuario-Hotels.d553248635943694289.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEl-Santuario-Hotels.d553248635943694289.Travel-Guide-Hotels) ## Learn more about El Santuario Check out San Nicolás Mall and Comfama Tutucán Recreational Park—just a couple of the sights around El Santuario. [See all hotels in El Santuario](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-14&endDate=2026-04-15&adults=2®ionId=553248635943694289) ![El Santuario, Antioquia, Colombia. June 28, 2025. Panoramic drone view of the town's main church.](https://images.trvl-media.com/place/553248635943694289/ad22c12c-1309-48b4-89f4-e7d9c5e76429.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top El Santuario Hotel Reviews ![NH Collection Medellín Royal](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/a8577ee4_y.jpg) ### NH Collection Medellín Royal 6/10 Okay "The location of the hotel was perfect, very close to Santa Fe Shopping Mall. Breakfast was great with lots of choice in both local and international options. The hotel itself I found a bit outdated. The floor of our room (415) had marks and spots on it which, at first glance upon arrival, makes you think that the room had not been cleaned. The mirrors as well had fingerprints on it. " [](https://expedia.co.uk/Medellin-Hotels-NH-Collection-Medellin-Royal.h1946355.Hotel-Information) ![Blues Suites Medellin](https://images.trvl-media.com/lodging/92000000/91200000/91193400/91193367/b09866e8_y.jpg) ### Blues Suites Medellin 10/10 Excellent "No iba a medellin desde el año pasado y me encanto olver. Nada ha cambiado, el hotel impecable, buenas camas y buen desayuno." [](https://expedia.co.uk/Medellin-Hotels-Blues-Suites-Medellin.h91193367.Hotel-Information) ![Diez Hotel Categoria Colombia](https://images.trvl-media.com/lodging/4000000/3850000/3843900/3843830/8465784b_y.jpg) ### Diez Hotel Categoria Colombia 10/10 Excellent "Best hotel ever in Medellin. Great location just in front on Provenza and Lleras Park. Got a Spa, Sishi Restaurant and Arabian Original Food also. Best important a Money Exchange above inside the hotel near the lobby. Highly Recommended for family too." [](https://expedia.co.uk/Medellin-Hotels-Diez-Hotel-Categoria-Colombia.h3843830.Hotel-Information) ![Calle Flora Hotel by Jalo](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/2f799eb1_y.jpg) ### Calle Flora Hotel by Jalo 10/10 Excellent "Excelente ubicación " [](https://expedia.co.uk/Medellin-Hotels-Jalo-Calle-Flora-Hotel.h117576751.Hotel-Information) ![Heiss Hotel By Jalo](https://images.trvl-media.com/lodging/106000000/105650000/105647300/105647272/98c427b6_y.jpg) ### Heiss Hotel By Jalo 8/10 Good "Very lovely staff, with the exception of room service staff. Not sure the name of this lady, however she was very condescending and rude. Essentially angry that she could not do the cleaning since we had the do not disturb sign on the door. Frankly, with a bit of kindness one can go a long way especially with how you speak to your guests. If there was ever an issue, it could have been communicated in a more appropriate matter. Besides that, the other staff were very kind, helpful and professional. " [](https://expedia.co.uk/Medellin-Hotels-Hotel-Heiss.h105647272.Hotel-Information) ![Hotel Provenza Garden](https://images.trvl-media.com/lodging/7000000/6020000/6010100/6010037/5f992a18_y.jpg) ### Hotel Provenza Garden 10/10 Excellent "El lugar super por q estas en el ambiente perfecto para disfrutar ! Negocios comida mini market etc discotecas ! Los empleados super amables ! Habitaciones un poco pequeñas pero muy limpias y perfectas para lo que yo estaba buscando 💪 sin duda me quedaría nuevamente sin pensarlo 💪" [](https://expedia.co.uk/Medellin-Hotels-MS-Hotel-Natura-Express.h6010037.Hotel-Information) ![Hotel Park 10](https://images.trvl-media.com/lodging/1000000/30000/28700/28652/20155102_y.jpg) ### Hotel Park 10 10/10 Excellent "The breakfast was fresh daily the fruits pastry and juices " [](https://expedia.co.uk/Medellin-Hotels-Hotel-Park-10.h28652.Hotel-Information) ![V Grand Hotel, a member of Radisson Individuals](https://images.trvl-media.com/lodging/17000000/16090000/16086300/16086237/6c551cf4_y.jpg) ### V Grand Hotel, a member of Radisson Individuals 8/10 Good "." [](https://expedia.co.uk/Medellin-Hotels-Viaggio-Medellin-Grand-Select.h16086237.Hotel-Information) ![Landmark Hotel](https://images.trvl-media.com/lodging/113000000/112590000/112583000/112582996/8567b7ef_y.jpg) ### Landmark Hotel 10/10 Excellent "Hotel property was beautiful. We loved the “smash” restaurant at the front for fresh squeezed juice. We would return! " [](https://expedia.co.uk/Medellin-Hotels-Landmark-Hotel.h112582996.Hotel-Information) ## More cheap stays in El Santuario ![Kromatic Hostel](https://images.trvl-media.com/lodging/103000000/102950000/102941100/102941048/w1920h2559x0y0-b65770a3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Kromatic Hostel 42 - 10 Cl. 49 Medellín Antioquia £14 1 Apr - 2 Apr additional charges may apply 7.4/10 Good! (30 reviews) [](https://expedia.co.uk/Medellin-Hotels-Kromatic-Hostel.h102941048.Hotel-Information) ![Hostal Lleras Calle 8 - Hostel](https://images.trvl-media.com/lodging/10000000/9400000/9395300/9395289/1ccf662a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Lleras Calle 8 - Hostel Calle 8 # 37A - 59 Medellín Antioquia £16 6 Apr - 7 Apr additional charges may apply [](https://expedia.co.uk/Medellin-Hotels-Hostal-Lleras-Calle-8.h9395289.Hotel-Information) ![Leviu by Bernalo Hotels](https://images.trvl-media.com/lodging/106000000/105860000/105850400/105850372/c2c9dda6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Leviu by Bernalo Hotels #31a-186 Cl. 11B Medellín Antioquia £37 5 Apr - 6 Apr additional charges may apply 8.6/10 Excellent! (126 reviews) [](https://expedia.co.uk/Medellin-Hotels-HOTEL-LEVIU.h105850372.Hotel-Information) ![Masaya Medellin](https://images.trvl-media.com/lodging/61000000/60650000/60649800/60649728/f66792ea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Masaya Medellin 43a1 Cl. 8 Medellín Antioquia £48 6 Apr - 7 Apr additional charges may apply 9.2/10 Wonderful! (174 reviews) [](https://expedia.co.uk/Medellin-Hotels-Masaya-Hostels-Medellin.h60649728.Hotel-Information) ![Nakúa Stay + Work](https://images.trvl-media.com/lodging/97000000/96280000/96274200/96274184/8b6d75ae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Nakúa Stay + Work 8A-29 Cra. 34 Medellín Antioquia £51 5 Apr - 6 Apr additional charges may apply 9.4/10 Exceptional! (138 reviews) [](https://expedia.co.uk/Medellin-Hotels-Cra-34-N-8A-29.h96274184.Hotel-Information) ![Golden Valley Hotel](https://images.trvl-media.com/lodging/106000000/105420000/105415800/105415734/36d0269d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Golden Valley Hotel Calle 9 # 43C - 32 Medellín Antioquia £61 1 Apr - 2 Apr additional charges may apply 9.2/10 Wonderful! (117 reviews) [](https://expedia.co.uk/Medellin-Hotels-Golden-Valley-Hotel.h105415734.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in El Santuario? > This area is the heart of El Santuario, where you'll find most of the town's shops, eateries, and local life. The Parque Principal is a pleasant green space, often bustling with activity, and features the impressive Basílica Menor de Nuestra Señora de Chiquinquirá. The surrounding streets are easily walkable and offer a real sense of the local culture. > > > For solo travellers or those looking to experience the local culture directly, staying near the Parque Principal is an excellent choice. You'll be within easy reach of local markets, traditional Colombian restaurants, and the town's main attractions, making it simple to explore on foot and connect with the community. > > > Couples seeking a convenient and authentic stay will also appreciate the town centre. ### When is the best time to go to El Santuario? > During these months, you'll experience more sunshine and less rain, making it ideal for exploring the town and its surroundings. The weather is generally pleasant, with comfortable temperatures, great for enjoying outdoor activities and day trips to nearby attractions. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a El Santuario hotel booking with Expedia? ### How much is the nightly rate at a El Santuario hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Holiday Homes - Other - [3 Star Hotels in Guatapé ](https://www.expedia.co.uk/3Star-Guatape-Hotels.s30-0-d6154953.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Guatapé ](https://www.expedia.co.uk/4Star-Guatape-Hotels.s40-0-d6154953.Travel-Guide-Filter-Hotels) - [5 Star Hotels in El Carmen de Viboral ](https://www.expedia.co.uk/5Star-El-Carmen-De-Viboral-Hotels.s50-0-d3000397191.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Guatapé ](https://www.expedia.co.uk/5Star-Guatape-Hotels.s50-0-d6154953.Travel-Guide-Filter-Hotels) - [Alejandria Hotels ](https://www.expedia.co.uk/Alejandria-Hotels.d6345924.Travel-Guide-Hotels) - 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