Most Popular Hotels in Downtown San Francisco

See all 139 Hotels in Downtown San Francisco
Nectar Logo

Get 200 Nectar points when you book your hotel

Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.

Serrano Hotel
Serrano Hotel

405 Taylor St, San Francisco 94102

4.0 out of 5.0
4.1 out of 5 (3,930 reviews)

The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks …

£125
Handlery Union Square Hotel
Handlery Union Square Hotel

351 Geary St, San Francisco 94102

3.5 out of 5.0
4 out of 5 (4,089 reviews)

A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the …

£125
Stanford Court San Francisco
Stanford Court San Francisco

905 California Street, San Francisco 94108

4.0 out of 5.0
4.2 out of 5 (2,645 reviews)

Guests can indulge in high-end shops like Prada and Tiffany & Co at Union Square, 4 blocks away. Chinatown is 5 minutes on …

£113
Clift
Clift

495 Geary St, San Francisco 94102

4.0 out of 5.0
4.2 out of 5 (3,505 reviews)

Old-world elegance is suffused with modern glamour in this historic San Francisco hotel 2 blocks from Union Square, a …

£157
Hotel Nikko San Francisco
Hotel Nikko San Francisco

222 Mason St, San Francisco 94102

4.0 out of 5.0
4.3 out of 5 (6,229 reviews)

The Asian-inspired Hotel Nikko San Francisco is located downtown, a 4-minute walk from Union Square and the designer shops of …

£261
Warfield Hotel
Warfield Hotel

118 Taylor St, San Francisco 94102

3.0 out of 5.0

Located in Downtown San Francisco, this inn is within a 15-minute walk of Westfield San Francisco Centre, Union Square, and …

£65
Four Seasons Hotel San Francisco
Four Seasons Hotel San Francisco

757 Market St, San Francisco 94103

5.0 out of 5.0
4.5 out of 5 (407 reviews)

Union Square, the Museum of Modern Art, San Francisco Shopping Centre, the Moscone Center, and cable cars are all within 2 to …

£367
The Marker San Francisco, a Joie de Vivre Hotel
The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco 94102

4.0 out of 5.0
4.4 out of 5 (1,921 reviews)

Eclectically decorated The Marker San Francisco, a 1910 Beaux Arts building, is within 2 blocks of Union Square and the Curra …

£129
Warwick San Francisco
Warwick San Francisco

490 Geary St, San Francisco 94102

4.0 out of 5.0
4.1 out of 5 (1,163 reviews)

This richly restored boutique hotel is in downtown San Francisco, across from the Curran and ACT theaters, 2 blocks from Unio …

£131
Kensington Park Hotel
Kensington Park Hotel

450 Post St, San Francisco 94102

3.5 out of 5.0
4.1 out of 5 (1,878 reviews)

Built in a Spanish Gothic style, this boutique hotel on San Francisco's Powell Street Cable Car Line lies in the theater an …

£126

Recent Reviews in Downtown San Francisco

Hide content

Narrow your search

Pocket Guide: Downtown San Francisco

Search for hotels in Downtown San Francisco on Expedia.co.uk. You can easily find your hotels in Downtown San Francisco using one of the methods below:

  • View our selection of featured hotels in Downtown San Francisco
  • Use the map to find hotels in the Downtown San Francisco neighborhood you prefer
  • Use the filters to see hotels in a specific area of Downtown San Francisco, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown San Francisco
  • Enter your travel dates to view the best deals on hotels in Downtown San Francisco - while they last
false