Most Popular Hotels in Downtown San Francisco

See all 170 Hotels in Downtown San Francisco
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Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco 94102

4.0 out of 5.0
4.3 out of 5 (6,452 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Westfield San Francisco Centre, San …

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Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco 94104

5.0 out of 5.0
4.6 out of 5 (325 reviews)

Offering spectacular views, this luxury hotel occupies the top floors of a 48-story tower in San Francisco's Financial …

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Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco 94102

3.5 out of 5.0
4 out of 5 (4,720 reviews)

A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the …

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Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco 94102

4.0 out of 5.0
4 out of 5 (4,338 reviews)

The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks …

£96
Staypineapple at The Alise San Francisco

Staypineapple at The Alise San Francisco

580 Geary St, San Francisco 94102

4.0 out of 5.0
4.5 out of 5 (368 reviews)

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Powell and Market Cable Car Turnaround and …

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The Adrian

The Adrian

493 Eddy St, San Francisco 94109

2.5 out of 5.0

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Asian Art Museum of San Francisco and Westfield …

£73
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco 94102

3.0 out of 5.0
4.3 out of 5 (4,738 reviews)

Located in Downtown San Francisco, this hotel is within a 15-minute walk of Powell and Market Cable Car Turnaround, San …

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Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco 94102

4.0 out of 5.0
4.4 out of 5 (527 reviews)

Located in Downtown San Francisco, this hotel is within a 15-minute walk of Westfield San Francisco Centre, San Francisco …

£112
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco 94102

4.0 out of 5.0
4 out of 5 (3,477 reviews)

This family-friendly San Francisco hotel is located in the entertainment district, within a 10-minute walk of Westfield San …

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The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco 94102

4.0 out of 5.0
4.4 out of 5 (2,161 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Westfield San Francisco Centre, San …

£135

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Pocket Guide: Downtown San Francisco

Life in Downtown San Francisco, CA

Anything goes in the spaces between the Transamerica Pyramid and Pier 39. Downtown welcomes the pierced, the polished, and the curious. If the delicious cuisine here doesn’t melt your taste buds, the eccentric art will melt your heart. Joggers, street performers, and vacationing families crawl the sloping streets with glee and determination. Whispers of a live band or a book signing at a local coffee shop get trapped in the iron gates and manicured walkways outside Victorian houses. Will you be there to soak up Downtown San Francisco’s pulsating energy? Let Expedia’s deals on Downtown San Francisco hotels show you why the West Coast is still a little crazy after all these years.

Weather on the Bay

There’s much to be said about the way the Pacific Ocean’s cool currents create a wonderfully unique climate here. Throw the windows open at one of the San Francisco hotels Downtown visitors love most to let a sweet Pacific breeze envelope your room. During summer, the bay’s famously magical fog creeps over downtown. Temperatures from May to October rarely move past 17 degrees Celsius. This coolness makes hiking up hills quite easy. The temperatures in November through April only dip to around 11 degrees Celsius.

Top Ways to Enjoy Downtown San Francisco

Union Square embodies the heart of the city. Linger near the plaza for live music, great shopping, and great access to restaurants. Journey to Coit Tower, San Francisco City Hall, and Fisherman's Wharf to be in the centre of the action. The San Francisco Zoo and Steinhart Aquarium are just a short jog away from Downtown San Francisco hotels.

Plan a Cheap Holiday in Downtown San Francisco

Use our discounts to pamper yourself to a stay at one of the city’s awesome boutique hotels without feeling guilty. Looking for a way to squeeze a flight to San Francisco International Airport (SFO) into your budget? Use our deals on cheap flights to Downtown San Francisco to experience the West Coast’s best attractions without breaking the bank. Book the lowest rates at San Francisco hotels with your friends at Expedia today.

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