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Top Downtown San Francisco Neighborhoods for Business Hotels

Union Square
1 hotels

The Mosser

2.5 out of 5.0
from

£62

South of Market
52 hotels

Hotel Whitcomb

3.5 out of 5.0
from

£83

Civic Center
3 hotels
from

£67

Featured Downtown San Francisco Business Hotels

See all 183 Hotels in Downtown San Francisco
The Mosser

The Mosser

54 4th Street, San Francisco
2.5 out of 5.0
3.9 out of 5 (5,191 reviews)
In the heart of downtown San Francisco. Close to everything in the heart of downtown San Francisco. The staff was extremely friendly and very helpful. Accessible to shopping, transit system, and many restaurants. Room was extremely clean-looked to be newly renovated. Be aware-no fridge or vending machines. Great for the value.
  22 Nov 2017

£62

£62
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

55 Cyril Magnin St, San Francisco
4.0 out of 5.0
4.2 out of 5 (11,419 reviews)
Good location and clean hotelGood location, clean room. The only and very bad point is that the hotel room not sound proof enough from street noises. Awoken us many times in the wee hours.
  23 Nov 2017

£101

£101
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (4,483 reviews)
Super nice, got upgraded from the 10th floor to the 31st floor!
  24 Nov 2017

£122

£122
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (6,469 reviews)
Love it here This is our second time at the NIkko in 3 months. Last time was with a client and this time just for us. We love it here. The staff is fantastic, rooms lovely and the valet and concierge, the very best! Thank you !
  20 Nov 2017

£133

£133
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.3 out of 5 (8,179 reviews)
Decent hotel very close to the BART station. Rolando at the front desk was very helpful. The front desk was busy with convention guests but he took his time answering my questions and helping me with an early check out.
  21 Nov 2017

£83

£83
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.0 out of 5.0
4.4 out of 5 (2,184 reviews)
Nice and close to union sqrCloser to union square with tea and wine time with a confortable chimeney
  21 Nov 2017

£135

£135
Marriott Courtyard San Francisco Downtown

Marriott Courtyard San Francisco Downtown

299 2nd St, San Francisco
3.5 out of 5.0
4.3 out of 5 (1,890 reviews)
Constuction!!!Wonderful hotel, great place for easy walking to union square, Chinatown, fisherman’s warf. However, they started construction at 7am in the room right above us everyday of the week!!!!!! Horrible!
  16 Nov 2017

£116

£116
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,447 reviews)
A historic gem in a diverse neighborhood.Surprise fees for “urban taxes” of $26+ were laughable. Hotel is actively renovating, which will only enhance its charm. On checkout day hotel was receiving large order of new mattresses. Looking up!
  19 Nov 2017

£102

£102
The Park Central San Francisco

The Park Central San Francisco

50 3rd St, San Francisco
4.0 out of 5.0
4.3 out of 5 (7,481 reviews)
Affordable and central locationThe hotel was a very reasonable price for the area. Storing a car was also very easy. We could get onto all the trolley/ bus lines we needed by a 1 block walk! Very pleased!
  23 Nov 2017

£84

£84
The Cartwright Hotel - Union Square BW Premier Collection

The Cartwright Hotel - Union Square BW Premier Collection

524 Sutter Street, San Francisco
3.5 out of 5.0
3.9 out of 5 (2,758 reviews)
Staff very good,,and convenience ,,clean roomVery convenient for restaurants, shopping, bus,cables car,, Rooms it's clean,,staff very nice,, I will come back
  22 Nov 2017

£83

£83
Map

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Pocket Guide: Business Hotels in Downtown San Francisco

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