Beginning of main content

Boutique Hotels in Downtown San Francisco, San Francisco

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Downtown San Francisco Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Downtown San Francisco Boutique Hotels

See all 179 Hotels in Downtown San Francisco
Kensington Park Hotel

Kensington Park Hotel

450 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (709 reviews)
Hotel within walking distance to Union SquareHotel do need some reno, rather dated. Beds are comfortable and the tea/sherry facility in the morning and evening is a nice touch. Very close to Union Square shopping area and lots of eateries around it. Morton is just next door and food is good but pricey.
  13 Jul 2017

£145

£145
Hotel Abri - Union Square

Hotel Abri - Union Square

127 Ellis Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (835 reviews)
Great place to stay in San Francisco!We absolutely loved this hotel! We received two bottles of water, and a bottle of wine at check in! The rooms are not big but were very comfortable, and clean. At check out staff helped bring our bags out to the car. There was a bit of a delay opening the restaurant in the morning, but that was the ...
  21 Jul 2017

£136

£136
Clift

Clift

495 Geary St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,400 reviews)
From the moment we arrived, the hotel staff were very accommodating and friendly. On the quiet side considering near Union Square and a lot of people and traffic. Easy walk to everything. Only downside was the construction on the exterior of the building during our stay.
  18 Jul 2017

£146

£146
Mystic Hotel by Charlie Palmer

Mystic Hotel by Charlie Palmer

417 Stockton St, San Francisco
3.5 out of 5.0
3.9 out of 5 (653 reviews)
Eclectic beauty Stay was nice. Location was good. Cozy eclectic place. Very clean.
  12 Jul 2017

£148

£148
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (565 reviews)
most staff are nice but door man was rude & make me feel unconfortable.
  4 Jul 2017

£246

£246
Hotel Diva

Hotel Diva

440 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (702 reviews)
Nice euro style hotel near Union Square.Easy to access, central location, had all accommodations necessary and price was good.
  16 Jul 2017

£154

£154
Villa Florence

Villa Florence

225 Powell St, San Francisco
4.0 out of 5.0
3.7 out of 5 (525 reviews)
Nice and quiet place, in a great location. Everything is in a walking distance, attractions, restaurants and shops.
  17 Jul 2017

£171

£171
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.0 out of 5.0
4.4 out of 5 (945 reviews)
Great Hotel with Amazing StyleI loved my recent stay at the Marker. It was a great location, and you can't beat how stylish the rooms are. I love a hotel with character and this one definitely has a ton! There is an extra charge daily for extra amenities, so be ready to pay an extra ~$20 per day. The staff was excellent!
  17 Jul 2017

£177

£177
Hotel Rex, a Joie de Vivre Boutique Hotel

Hotel Rex, a Joie de Vivre Boutique Hotel

562 Sutter St, San Francisco
3.5 out of 5.0
4.2 out of 5 (502 reviews)
Always stay here when visiting sf.Staff always helpful..close to shopping, entertainment, ect. Few mins away from wharf. Love the history about hotel itself. We always stay here when visiting bay area.
  13 Jul 2017

£163

£163
Inn At Union Square

Inn At Union Square

440 Post St, San Francisco
3.5 out of 5.0
4.6 out of 5 (433 reviews)
Hotel in an excellent location!!! Perfect location to base yourself for sightseeing. The hotel was cozy and clean. The room was well- appointed but slightly warm (there is no air con), but there is a fan. Breakfast was a nice inclusion. Would visit again.
  10 Jul 2017

£253

£253
Map

Recently booked Downtown San Francisco hotels

Stanford Court San Francisco
4.0 out of 5.0
Last booking: 8 minutes ago
Grand Hyatt San Francisco Union Square
4.0 out of 5.0
Last booking: 18 minutes ago
The Urban
2.5 out of 5.0
Last booking: 19 minutes ago
Handlery Union Square Hotel
3.5 out of 5.0
Last booking: 21 minutes ago
Civic Center Motor Inn
2.0 out of 5.0
Last booking: 24 minutes ago
San Francisco Marriott Union Square
4.0 out of 5.0
Last booking: 26 minutes ago
The Westin St Francis San Francisco on Union Square
4.0 out of 5.0
Last booking: 27 minutes ago
Hotel EPIK
3.5 out of 5.0
Last booking: 29 minutes ago
Clift
4.0 out of 5.0
Last booking: 37 minutes ago

Pocket Guide: Boutique Hotels in Downtown San Francisco

Search for hotels in Downtown San Francisco on Expedia. You can easily find your hotels in Downtown San Francisco using one of the methods below:

  • View our selection of featured hotels in Downtown San Francisco
  • Use the map to find hotels in the Downtown San Francisco neighborhood you prefer
  • Use the filters to see hotels in a specific area of Downtown San Francisco, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown San Francisco
  • Enter your travel dates to view the best deals on hotels in Downtown San Francisco - while they last