Cherokee Holidays

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    Packages with flights are ATOL protected

Cherokee Essential Information

Language
English
Currency
U.S dollars
Population
5,000
Max Temp Winter
-3.89ºC
Max Temp Summer
27ºC

Top hotels in Cherokee

Best Western La Grande Hacienda

Best Western La Grande Hacienda

2.5 out of 5
1401 N 2nd Street, Cherokee, IA
Fully refundableReserve now, pay when you stay
The price is £87 per night from 10 Aug to 11 Aug
£87
10 Aug - 11 Aug
includes taxes & fees
7.6/10 Good! (336 reviews)
"The hotel and staff were great. Convenient location for dining (excellent Mexican restaurant next door), gas, groceries, other restaurants nearby. Parking was easy and right next to the entrance. But the pool was going through some maintenance while we were there, and it was ice cold the one night ..."

Reviewed on 28 Jul 2025

Best Western La Grande Hacienda
Cherokee Vacation Rental - On Main Street!

Cherokee Vacation Rental - On Main Street!

3 out of 5
Cherokee, IA
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Cherokee Vacation Rental - On Main Street!
Downtown Cherokee Iowa Vacation Rental

Downtown Cherokee Iowa Vacation Rental

3 out of 5
Cherokee, IA
"Perfect little place to stay; tried too book again but was full. 10/10 would use this place again"

Reviewed on 25 Sep 2024

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Downtown Cherokee Iowa Vacation Rental
See all 32 properties in Cherokee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

Why should I book my Cherokee holiday with Expedia?
Expedia has your back for every detail of your next Cherokee getaway. You'll always land the best deals, but when you bundle your flights, accommodation and/or hire car into a holiday package, you'll get even more savings. Want to truly make the most of your break? Add some exciting activities and tours to your package. Expedia offers flexible cancellation policies on almost all bookings, so you won't need to worry if you have to change your plans. Visit our Customer Service Portal link to learn more.
When is the best time of year to holiday in Cherokee?
Cherokee is a busy place in May, July and September. If you don't like large crowds and prefer a slower pace, lock in your trip for April, August and December. With average daytime temperatures of -7ºC, January is the coolest period in Cherokee. The warmest month is July, when you can expect average temperatures of 23ºC throughout the day. Whatever the weather conditions, you'll find a whole lot to keep you entertained here.
What is the top hotel for my holiday in Cherokee?
Offering many of the conveniences and comforts of home, Hotel Fort Des Moines, Curio Collection by Hilton will make the perfect base for your Cherokee escape.
How do I get a cheap holiday to Cherokee?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a few pounds too. A Cherokee holiday makes it a cinch to create your ideal trip. With more than 400 airlines across the world to select from, finding flights that fit your schedule won't be an issue. Not only that, we have over 321,000 properties globally to pick from. Talk about choice! Whatever your budget, Expedia will help show you the world. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my Cherokee holiday?
There are lots of places to visit while having a holiday in Cherokee. Cherokee Regional Clinics, Gillette Park, Sanford Museum & Planetarium and Cherokee Depot are among this destination's leading attractions.
Do I need a visa for my Cherokee holiday?
Look up the most up-to-date information on official government websites. Your nationality and whether you're visiting for business, leisure or study will determine if you'll require a visa for Cherokee. Familiarise yourself with the application process, including the required documentation, turnaround times and fees. Submit your application well in advance to allow enough time for processing. Some visas can take several weeks or even months to obtain, depending on the country.
What should I wear on my Cherokee holiday?
First, consider the types of activities you'll be doing during your holiday in Cherokee and select versatile pieces that you can easily mix and match. For fashion inspiration or information on any dress codes, browse a few style blogs or relevant social media accounts. Daytime temperatures during January, Cherokee's coolest month, average -7ºC. July marks this city's warmest month when the average reaches 23ºC. Our tip? Take the guesswork out of what to pack and check the weather forecast.
What does an Expedia Cherokee holiday include?
Expedia has all you need to lock in your Cherokee trip, but what goes into your package is totally up to you. Select from any combination of hotels, flights and hire cars. Searching for a few activities to keep you busy? Once you've made your booking, you can add them too. Whatever your style or budget, there's a holiday package to match your needs. Expedia features all types of properties, with the most sought after in Cherokee being apartments and hotels. With Expedia, you'll always enjoy the freedom and flexibility to tailor your holiday any way you like.
Does Expedia offer Book Now, Pay Later Cherokee holidays?
Expedia has joined forces with online lender Klarna to make booking your next trip a little easier on the wallet. Paying by instalment means you can spread the costs of your next big holiday, leaving you with more cash to spend while you're away. Klarna has several payment plans to pick from, so you're sure to find one that fits into your budget. Take a look at these flexible payment options:

  • Pay monthly holidays: If paying in multiple transactions sounds best for you, Klarna can help. Paying in easy monthly instalments will make your getaway dreams come true.
  • No-deposit holidays: If no upfront fee for your trip makes clicking that "book now" button easier, go for a no-deposit holiday plan from Klarna so you can Book Now, Pay Later!

Can I choose my airline with a Cherokee Expedia holiday?
Most definitely. Expedia has more than 400 airline partners to pick from globally. With all that choice, finding the right carrier to get you to Cherokee won't be hard.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.