Title: Cheap Flights to San Luis - Expedia.co.uk ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £48 Cheap Flights to San Luis [View £48 flight on Wed, 13 May 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:BOG,to:MDE,departure:13/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:47.10&airProductToken=AQowCi4IzIIBEgQ0MDM0GMEzIOwgKMb1jAMwgvaMAzhPQABYAWoCUVByCE8wMFFQR1pUEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) [Hotels in San Luis](https://expedia.co.uk/San-Luis-Hotels.d553248635943694119.Travel-Guide-Hotels)[San Luis Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis.d553248635943694119.Car-Hire-Guide)[San Luis Holidays](https://expedia.co.uk/San-Luis.d553248635943694119.Holidays-City-Breaks) ## Popular airlines to San Luis - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:San Luis, Antioquia, Colombia,departure:12/04/2026TANYT&leg2=from:San Luis, Antioquia, Colombia,to:CMH,departure:19/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AM"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to San Luis Prices were available within the past 7 days and start at £48 for one-way flights and £94 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Fri, 1 May - Sun, 3 May BOG Bogotá MDE Medellin £94 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:MDE,departure:01/05/2026TANYT&leg2=from:MDE,to:BOG,departure:03/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:93.20&airProductToken=AQowCi4IzIIBEgQ0MDI2GMEzIOwgKJbviwMw0u-LAzhPQABYAWoCUVByCE8wMFFQR1pUCjAKLgjMggESBDQwMDkY7CAgwTMoxf-LAzCGgIwDOE9AAFgBagJRUHIITzAwUVBHWlQSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Fri, 1 May - Sun, 3 May BOG Bogotá MDE Medellin £101 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:MDE,departure:01/05/2026TANYT&leg2=from:MDE,to:BOG,departure:03/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:100.20&airProductToken=AQozCjEIwawBEgQ5MzIyGMEzIOwgKK3uiwMw6e6LAzhTQABYAWoFQkFTSUNyCFNFT0IwSVJLCjMKMQjBrAESBDg0NzUY7CAgwTMor_6LAzD1_osDOFNAAFgBagVCQVNJQ3IIU0VPQjBJUksSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) ![Arajet](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DM.gif) Tue, 8 Sept - Tue, 15 Sept SDQ Santo Domingo MDE Medellin £159 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SDQ,to:MDE,departure:08/09/2026TANYT&leg2=from:MDE,to:SDQ,departure:15/09/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:158.88&airProductToken=AQo1CjMIxJoBEgQxNzM4GPKAASDsICjioZcDMPqilwM4waABQABYAWoFQkFTSUNyB0FQQkFTT1cKNQozCMSaARIEMTczNxjsICDygAEoie-XAzCh8JcDOMGgAUAAWAFqBUJBU0lDcgdBUEJBU09XEgoICxABGAgqAkRNGAEiBAgBEAEoAjAD) ![APG Distribution System](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/GP.gif) Sat, 18 Apr - Wed, 22 Apr BOG Bogotá EOH Medellin £162 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:EOH,departure:18/04/2026TANYT&leg2=from:EOH,to:BOG,departure:22/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:161.30&airProductToken=AQo0CjIIwWISBDU1NjMYwTMgxDsorNWKAzD31YoDOE1AAFgBcgVNT1dWRXoKCNaKARIENTU2Mwo0CjIIwWISBDU1NjQYxDsgwTMohoOLAzDHg4sDOE1AAFgBcgVNT1dWRXoKCNaKARIENTU2NBIKCAEQARgBKgJHUBgBIgQIARABKAIoAygEMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Tue, 7 Apr - Sat, 11 Apr SJO San José MDE Medellin £250 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SJO,to:MDE,departure:07/04/2026TANYT&leg2=from:MDE,to:SJO,departure:11/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:249.90&airProductToken=AQpECiAIw5oBEgMzNDEYsnIg78QBKKTciQMw-NyJAzhUQABYAQogCMOaARIDNzY0GO_EASDsICit3YkDMIHeiQM4VEABWAEKRAogCMOaARIDNzU3GOwgIO_EASiHiYoDMN-JigM4VEAAWAEKIAjDmgESAzM0MhjvxAEgsnIos4qKAzCIi4oDOFRAAVgBEgoIARABGAEqAkNNGAEiBAgBEAEoBDAB) ## Find the cheapest month to fly from Columbus (CMH) to Medellín (MDE) ### September is typically the cheapest month to fly From £195 - £497 per traveller. ## Frequently asked questions ### What is the name of San Luis' airport? ### How far is MDE from central San Luis? ### What airport is best to fly into San Luis? ### How many airlines fly to San Luis? ### Which airlines fly to San Luis? ### How many nonstop flights are there to San Luis? ### Where are the most popular flights to San Luis departing from? ### How long is the flight to San Luis Airport? ### How to book the cheapest flight to San Luis? ### Do you have any tips for my flight to San Luis? > - Air travel can be a pleasure if you take the right things. First things first, you'll need basic toiletry items, such as a toothbrush and hairbrush, a clean pair of socks and a magazine or two. Secondly, find a spot in your carry-on bag for your electronic gadgets, chargers, medications and maybe a proper neck pillow too. Lastly, and most importantly, be sure to bring your passport, travel docs and some cash. > > > Do not pack the following items in your hand luggage: > > > - While the list of restricted items can differ between airlines, the general guide to follow is nothing flammable, sharp or explosive. This includes screwdrivers, blades, fuels and bleaching agents. Sports equipment like golf clubs, and items that could harm passengers, such as guns and swords, won't be allowed on board either. > > > What to wear on a flight: > > > - You'll want to choose comfort over style. Prepare for changes in cabin temperature by donning layers, and wear flat, easy-to-remove footwear like slip-ons. > - You've probably heard about deep vein thrombosis (DVT), a blood clot condition caused by prolonged periods of sitting. To reduce your risk on board, drink plenty of water, consider wearing compression socks and keep your legs and feet moving. ### How to get through airport security fast when flying to San Luis? > - Airport security personnel first need to know that you have a valid ID and boarding pass before you can proceed any further. Have them in your hand, ready for inspection. > - Your belt, jacket, keys and other contents of your pockets, like your headphones, will need to go through the X-ray machine. Make your life easier by removing them as it gets closer to your turn. > - Your electronic devices like laptops and phones will also have to go on a tray for inspection. Don't worry though, you'll be back online before you know it. > - Travelling with your favourite hand and nail cream? No problem. As long as the volume is no larger than 3.4 ounces (100 millilitres) and it's stored in a clear zip-close bag, it's OK to bring with you in your carry-on baggage. > - There's a chance you'll need to take your shoes off to be X-rayed, so wearing slip-on sneakers is always a wise idea. > - Airlines will not allow any sharp items or pocket knives in your carry-on baggage. If you must bring these kinds of items, check them in. ## Book with confidence # Expedia flights to San Luis Searching for cheap flights to San Luis? No travel company presents more choices than Expedia if you're looking to compare flights to San Luis. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Antioquia. Expedia provides the cheapest flights to many destinations in Antioquia and you may find even greater savings if you combine your flight with a hotel stay in San Luis. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to San Luis for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your San Luis flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Travel information | Destination airport | José María Córdova Intl. | | ----------------------------- | ------------------------ | | Destination airport IATA code | MDE | | Destination city name | Medellín | | Return price | £93 | ## Trending flights to San Luis Prices were available within the past 7 days and start at £48 for one-way flights and £94 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Thu, 7 May - Thu, 25 Jun LHR London MDE Medellin £693 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:MDE,departure:07/05/2026TANYT&leg2=from:MDE,to:LHR,departure:25/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:692.75&airProductToken=AQqpAQozCMuYARIEMTAwMhjriQEggJMBKOypjAMwvKqMAzhMQABYAWoFTElHSFRyCEdHTERJN0xJCjIIy5gBEgM3NTcYgJMBIO_EASivq4wDML6wjAM4R0ABWAFqBUxJR0hUcghHR0xESTdMSQo-CMuYARIEODg4NRjvxAEg7CAoo7GMAzD3sYwDOFZAAVgBagVMSUdIVHIIR0dMREk3TEl6CgjDmgESBDg4ODUKqQEKPgjLmAESBDg4ODYY7CAg78QBKPrWkAMw0deQAzhWQABYAWoFTElHSFRyCEdHTERJN0xBegoIw5oBEgQ4ODg2CjIIy5gBEgM3NTgY78QBIICTASjW2JADMMLdkAM4R0ABWAFqBUxJR0hUcghHR0xESTdMQQozCMuYARIEMTAwORiAkwEg64kBKI3ekAMw4t6QAzhMQAFYAWoFTElHSFRyCEdHTERJN0xBEgoIAhABGAIqAktMGAEiBAgBEAEoAigDKAQwDQ) \*Available to Expedia members.