Title: Cheap Flights to Knoxville - Expedia.co.uk ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £166 Cheap Flights to Knoxville [View £166 flight on Tue, 3 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SAN,to:DSM,departure:03/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:165.90&airProductToken=AQpsCi4IwaYBEgQxNDk1GJJoIK4cKOPShgMw6tSGAzhRQABYAWoCUE1yCFFXQUlLTk0zCjoIwaYBEgQ0NDkzGK4cIMNkKIzWhgMw4daGAzhRQAFYAWoCUE1yCFFXQUlLTk0zegoIwYIBEgQ0NDkzEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in Knoxville](https://expedia.co.uk/Knoxville-Hotels.d55779.Travel-Guide-Hotels)[Knoxville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Knoxville.d55779.Car-Hire-Guide)[Knoxville Holidays](https://expedia.co.uk/Knoxville.d55779.Holidays-City-Breaks) ## Popular airlines to Knoxville - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Knoxville, Iowa, United States of America,departure:31/01/2026TANYT&leg2=from:Knoxville, Iowa, United States of America,to:CMH,departure:07/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Knoxville Prices were available within the past 7 days and start at £166 for one-way flights and £344 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Fri, 30 Jan - Sat, 7 Feb SAN San Diego DSM Des Moines £344 Return found 19 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:DSM,departure:30/01/2026TANYT&leg2=from:DSM,to:SAN,departure:07/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:343.60&airProductToken=AQpFCiAIxJgBEgM3NTQYkmgg47QBKNfpgwMw5uuDAzhFQABYAQohCMSYARIENTM0NRjjtAEgw2Qo6-yDAzDs7YMDOEVAAVgBCkUKIQjEmAESBDU0OTgYw2Qg47QBKNHFhAMwwMaEAzhFQABYAQogCMSYARIDMzY5GOO0ASCSaCiux4QDMN7JhAM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, 30 Jan - Fri, 6 Feb CLD Carlsbad DSM Des Moines £393 Return found 19 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:CLD,to:DSM,departure:30/01/2026TANYT&leg2=from:DSM,to:CLD,departure:06/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:393.00&airProductToken=AQpoCjIIwYIBEgQ0MjI3GOIaIO-5ASjj6YMDMLXqgwM4QkAAWAFqBUJBU0lDcghHN0FXWk5CWAoyCMGCARIEMzEyMBjvuQEgw2Qo--qDAzCk7IMDOEJAAVgBagVCQVNJQ3IIRzdBV1pOQlgKaAoyCMGCARIEMjA4NxjDZCDvuQEosruEAzD3vIQDOEJAAFgBagVCQVNJQ3IIVlVBSVpOQloKMgjBggESBDQyMjYY77kBIOIaKLe9hAMwgr6EAzhCQAFYAWoFQkFTSUNyCFZVQUlaTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Fri, 23 Jan - Fri, 30 Jan DUB Dublin DSM Des Moines £440 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DUB,to:DSM,departure:23/01/2026TANYT&leg2=from:DSM,to:DUB,departure:30/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:439.50&airProductToken=AQq1AQoyCMuYARIEMTEzNBiDDSCAkwEog5eDAzDnl4MDOExAAFgBagVMSUdIVHIIVllMNlRWTEkKPwjLmAESBDYxMjAYgJMBIOO0ASjjmoMDMISfgwM4VkABWAFqBUxJR0hUcghWWUw2VFZMSXoKCMSYARIENjEyMAo-CMuYARIENjcyNBjjtAEgw2Qo8p-DAzDuoIMDOFZAAVgBagVMSUdIVHIIVllMNlRWTEl6CgjEmAESBDY3MjQKswEKPQjLmAESBDU5MjEYw2QgzHwo--qDAzDH64MDOFZAAFgBagVMSUdIVHIIVllMNlRWTEl6CgjEmAESBDU5MjEKPgjLmAESBDYwNjQYzHwggJMBKIrtgwMw_vCDAzhWQAFYAWoFTElHSFRyCFZZTDZUVkxJegoIxJgBEgQ2MDY0CjIIy5gBEgQxMTM5GICTASCDDSi084MDMJj0gwM4TEABWAFqBUxJR0hUcghWWUw2VFZMSRIKCAIQARgCKgJLTBgBIgQIARABKAIoAygEMA0) ![WestJet](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/WS.gif) Sun, 22 Mar - Wed, 25 Mar YYZ Toronto DSM Des Moines £512 Return found 5 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:YYZ,to:DSM,departure:22/03/2026TANYT&leg2=from:DSM,to:YYZ,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:511.20&airProductToken=AQp_Cj4I16YBEgQ2MzUzGJjOASDMfCjWpYgDMPemiAM4WEAAWAFqBUVDT05PcghYT1VEMFpFU3oKCMSYARIENjM1Mwo9CNemARIEODcxNhjMfCDDZCjuqYgDMLqqiAM4WEABWAFqBUVDT05PcghYT1VEMFpFU3oKCMSYARIEODcxNgqBAQo-CNemARIENzI3MRjDZCDjtAEo4MmIAzDLyogDOExAAFgBagVFQ09OT3IITE9RRDBaRUt6CgjEmAESBDcyNzEKPwjXpgESBDYzMTIY47QBIJjOASjvyogDMLzLiAM4TEABWAFqBUVDT05PcghMT1FEMFpFS3oKCMSYARIENjMxMhIKCAEQARgBKgJXUxgBIgQIARABKAIoAygEMAE) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Tue, 23 Jun - Tue, 14 Jul PRG Prague DSM Des Moines £661 Return found 17 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PRG,to:DSM,departure:23/06/2026TANYT&leg2=from:DSM,to:PRG,departure:14/07/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:660.56&airProductToken=AQqyAQoxCMKCARIDODU5GK80IOuJASiTuZADMJq6kAM4T0AAWAFqBU5PQkFHcghPS043VDhCVwo-CMKCARIEMTU0NBjriQEgrhwoo7yQAzCwwJADOE9AAVgBagVOT0JBR3IIT0tON1Q4Qld6CgjBggESBDE1NDQKPQjCggESBDY1MjkYrhwgw2Qo38GQAzC8wpADOE9AAVgBagVOT0JBR3IIT0tON1Q4Qld6CgjNogESBDY1MjkKsgEKPQjCggESBDY1MTgYw2Qgrhwo-q6SAzDar5IDOE9AAFgBagVOT0JBR3IIT0tON1Q4Qld6CgjNogESBDY1MTgKPgjCggESBDE2MDEYrhwg64kBKJewkgMw47OSAzhPQAFYAWoFTk9CQUdyCE9LTjdUOEJXegoIwYIBEgQxNjAxCjEIwoIBEgM4NTQY64kBIK80KKm0kgMwobWSAzhPQAFYAWoFTk9CQUdyCE9LTjdUOEJXEgoIARABGAEqAkJBGAEiBAgBEAEoAigDMA0) ## Find the cheapest month to fly from Columbus (CMH) to Des Moines (DSM) ### October is typically the cheapest month to fly From £135 - £415 per traveller. ## Expedia flights to Knoxville Searching for cheap flights to Knoxville? No travel company presents more choices than Expedia if you're looking to compare flights to Knoxville. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Iowa. Expedia provides the cheapest flights to many destinations in Iowa and you may find even greater savings if you combine your flight with a hotel stay in Knoxville. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Knoxville for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Knoxville flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Frequently asked questions ### What is the name of Knoxville's airport? ### What airport is best to fly into Knoxville? ### How many airlines fly to Knoxville? ### Which airlines fly to Knoxville? ### How many nonstop flights are there to Knoxville? ### Where are the most popular flights to Knoxville departing from? ### How long is the flight to Knoxville Airport? ### How to book the cheapest flight to Knoxville? ### Do you have any tips for my flight to Knoxville? > - Air travel can be a pleasure if you bring the right gear. First of all you'll need basic toiletry items, such as toothpaste, a toothbrush and some deodorant, a spare set of clothes and a good read. Next, find a spot in your bag for your phone, tablet and chargers, your important medications and maybe a quality neck pillow as well. Last, but definitely not least, remember to bring your passport, travel docs and some cash. > > > Do not pack the following items in your hand luggage: > > > - While the list of banned items differs between airlines, the general rule of thumb is avoid carrying anything flammable, sharp or explosive. This includes things like box cutters, razor blades, aerosol cans and flares. Sporting equipment like ski poles, and items that could injure passengers, such as firearms and ammunition, aren't allowed in the cabin either. > > > What to wear on a flight: > > > - Comfort should be your top priority when deciding what to wear during your flight. Loose clothing is a smart option, as are enclosed shoes like sneakers. > - Most travellers have heard about deep vein thrombosis (DVT), a blood clotting condition caused by prolonged periods of sitting. To reduce your risk on board, drink plenty of water, consider wearing compression socks or tights and keep your legs and feet moving. ### How to get through airport security fast when flying to Knoxville? > - Your travel documents and passport will need to be presented to airport security personnel. Have them close by so you don't have to dig around for them. > - Next up, both you and your hand luggage must be X-rayed. To speed things up, take off anything that might set the alarms off. Personal belongings such as your belt, coat and earphones need to go through the machine. > - All your electronic gadgets, including your laptop and phone, will also need to be scanned separately. > - Any gels or liquids, such as shampoo or hand cream, that you want to bring on board need to be in containers no greater than 3.4 ounces (100 millilitres). They must also all fit inside a quart-size (one litre), clear zip-lock bag. > - There's a possibility that you'll be required to take your shoes off for scanning, so wearing slip-on shoes is always a clever idea. > - Take all prohibited items out of your carry-on bag. If you have any sharp or pointed objects, put them in your checked suitcase. They won't be allowed on board and will be confiscated. __Flights to Knoxville information__ | Destination airport | Des Moines Intl. | | ----------------------------- | ---------------- | | Destination airport IATA code | DSM | | Destination city name | Des Moines | | Return price | £344 | ## Trending flights to Knoxville Prices were available within the past 7 days and start at £166 for one-way flights and £344 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Mon, 26 Jan - Thu, 29 Jan LHR London DSM Des Moines £695 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:DSM,departure:26/01/2026TANYT&leg2=from:DSM,to:LHR,departure:29/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:694.55&airProductToken=AQqqAQozCNOWARIDNTAwGOuJASDiOyiQuYMDMP65gwM4TkAAWAFqCFN0YW5kYXJkcgdOTEVVNkVTCjII05YBEgM5MjkY4jsg4Fwo37uDAzDBwIMDOE5AAVgBaghTdGFuZGFyZHIHTkxFVTZFUwo_CNOWARIEMzIzMBjgXCDDZCinwoMDMK3DgwM4TkABWAFqCFN0YW5kYXJkcgdOTEVVNkVTegoIxJgBEgQzMjMwCqsBCj8I05YBEgQzODA0GMNkIOBcKPbfgwMw9OCDAzhOQABYAWoIU3RhbmRhcmRyB05MRVU2RVN6CgjEmAESBDM4MDQKMgjTlgESAzkzMBjgXCDiOyi844MDMMTngwM4TkABWAFqCFN0YW5kYXJkcgdOTEVVNkVTCjQI05YBEgQxNTE3GOI7IOuJASis6oMDMKTrgwM4TkABWAFqCFN0YW5kYXJkcgdOTEVVNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwDw) \*Available to Expedia members.