Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Nectar
Collect Nectar points
Nectar
Collect Nectar points
Nectar
Collect Nectar points

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Central San Diego Independent Hotels

See all 267 Hotels in Central San Diego
Town and Country San Diego

Town and Country San Diego

500 Hotel Circle North, San Diego
    3.5 out of 5.0
     
     
    3.3 out of 5 (1,878 reviews)
    Good location and bad parking We booked this place for a last minute trip. When we arrived it was busy but the check in process w … - 

    Town and Country San Diego£79

    Town and Country San Diego£79
    Kings Inn San Diego - Seaworld - Zoo

    Kings Inn San Diego - Seaworld - Zoo

    1333 Hotel Cir S, San Diego
      2.5 out of 5.0
       
       
      3.9 out of 5 (4,711 reviews)
      Servicable hotel fairly neat seaworld Staff was friendly. Toilet was a little dirty (floor) but given the price can't complain. No lift. - 

      Kings Inn San Diego - Seaworld - Zoo£50

      Kings Inn San Diego - Seaworld - Zoo£50
      The Atwood

      The Atwood

      1201 Hotel Circle South, San Diego
        3.0 out of 5.0
         
         
        3.8 out of 5 (1,243 reviews)
        Friendly staff. Room was clean. Unfortunately the pool closes at 8pm. The pizza at the Crust Kitche … - 

        The Atwood£54

        The Atwood£54
        California Suites Hotel

        California Suites Hotel

        5415 Clairemont Mesa Blvd, San Diego
          2.0 out of 5.0
           
           
          3.3 out of 5 (1,933 reviews)
          Shower was not working well. I liked the privacy of the hotel which is located not far from histori … - 

          California Suites Hotel£43

          California Suites Hotel£43
          Handlery Hotel

          Handlery Hotel

          950 Hotel Cir N, San Diego
            3.5 out of 5.0
             
             
            3.6 out of 5 (30 reviews)
            Awesome! The hotel is a bit older so the rooms are not modern. But overall everything was great, the pool wa … - 

            Handlery Hotel£68

            Handlery Hotel£68
            Pleasant Inn

            Pleasant Inn

            5550 Clairemont Mesa Blvd, San Diego
              2.5 out of 5.0
               
               
              4.1 out of 5 (675 reviews)
              Nice Hotel. Nice, clean and neat hotel. Not much options available for breakfast. Standard facilities like othe … - 

              Pleasant Inn£46

              Pleasant Inn£46
              E-Z 8 Motel Old Town

              E-Z 8 Motel Old Town

              4747 Pacific Highway, San Diego
                2.5 out of 5.0
                 
                 
                3.0 out of 5 (607 reviews)
                Dog friendly Very friendly staff. Dog friendly. Can walk to old Town. - 

                E-Z 8 Motel Old Town£38

                E-Z 8 Motel Old Town£38
                The Lafayette Hotel, Swim Club & Bungalows

                The Lafayette Hotel, Swim Club & Bungalows

                2223 El Cajon Blvd, San Diego
                  3.5 out of 5.0
                   
                   
                  3.9 out of 5 (3,045 reviews)
                  Really nice bungalow and decent hotel facilities We stayed in one of the bungalows and were very happy with it. It had two floors and good size room … - 

                  The Lafayette Hotel, Swim Club & Bungalows£95

                  The Lafayette Hotel, Swim Club & Bungalows£95
                  Old Town Western Inn & Suites

                  Old Town Western Inn & Suites

                  3889 Arista St, San Diego
                    2.5 out of 5.0
                     
                     
                    3.3 out of 5 (912 reviews)
                    Great hidden gem. This hotel is great! It’s central to most desired destinations and it’s located in historic Old Own … - 

                    Old Town Western Inn & Suites£55

                    Old Town Western Inn & Suites£55
                    Hotel Iris - San Diego

                    Hotel Iris - San Diego

                    625 Hotel Cir S, San Diego
                      2.5 out of 5.0
                       
                       
                      3.3 out of 5 (716 reviews)
                      Decent for a quick 2 stay! Had to ask for more towels and there was no hand soap provided. - 

                      Hotel Iris - San Diego£48

                      Hotel Iris - San Diego£48

                      Recently booked Central San Diego hotels

                      Ramada San Diego North Hotel and Conference Center
                      3.5 out of 5.0
                      Last booking: 1 hour ago
                      Extended Stay America San Diego - Sorrento Mesa
                      2.5 out of 5.0
                      Last booking: 2 hours ago
                      Motel 6 San Diego North
                      2.0 out of 5.0
                      Last booking: 2 hours ago
                      Courtyard by Marriott San Diego Sorrento Valley
                      3.0 out of 5.0
                      Last booking: 3 hours ago
                      Best Western San Diego/Miramar Hotel
                      2.5 out of 5.0
                      Last booking: 5 hours ago
                      Pleasant Inn
                      2.5 out of 5.0
                      Last booking: 6 hours ago
                      California Suites Hotel
                      2.0 out of 5.0
                      Last booking: 7 hours ago
                      Extended Stay America San Diego - Mission Valley - Stadium
                      2.5 out of 5.0
                      Last booking: 8 hours ago
                      Four Points by Sheraton San Diego
                      3.0 out of 5.0
                      Last booking: 10 hours ago

                      Pocket Guide: Independent Hotels in Central San Diego

                      Search for hotels in Central San Diego on Expedia. You can easily find your hotels in Central San Diego using one of the methods below:

                      • View our selection of featured hotels in Central San Diego
                      • Use the map to find hotels in the Central San Diego neighborhood you prefer
                      • Use the filters to see hotels in a specific area of Central San Diego, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Central San Diego
                      • Enter your travel dates to view the best deals on hotels in Central San Diego - while they last