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Holidays to Cayo Santa Maria

Accommodation, flights, car rentals, things to do and more - for your holiday in Cayo Santa Maria choose Expedia! Find everything you need to organize your trip to Cayo Santa Maria in one place. Enter your dates in the search bar above or scroll to our top deals below!

Top flight + hotel deals in Cayo Santa Maria

Trump National Doral Miami
Hotel St Augustine
Nautilus by Arlo
The L Hotel
National Hotel, An Adult Only Oceanfront Resort
Beacon Hotel South Beach

Top Hotel Deals

Grand Memories Santa Maria - All Inclusive
Grand Memories Santa Maria - All Inclusive
3.5 out of 5
Municipio Caibarien, Cayo Santa Maria, Villa Clara

Nestled on the beach, this Cayo Santa Maria resort is 4.1 mi (6.5 km) from Playa Las Gaviotas and 4.8 mi (7.8 km) from Cayo Santa Maria Dolphinarium.

2.8/5 (78 reviews)

"beautiful beach and good food at the buffet despite long queues to get it. Room needs to be totally refurbished to be compared to an European 5 stars resort! However, the staying was pleasant!"…"

Reviewed on 28 Mar 2020

Grand Memories Santa Maria - All Inclusive
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
3.5 out of 5
Cayo Santa Maria, Cayo Santa Maria, Villa Clara

Nestled on the beach, this Cayo Santa Maria resort is 3.8 mi (6.2 km) from Playa Las Gaviotas and 5.2 mi (8.3 km) from Cayo Santa Maria Dolphinarium.

3.3/5 (47 reviews)

"The beach is beautiful, the food and drink are good and better than other hotels that I stayed before, but property conditions are not good, dirty walls, bad repairs, etc... rooms services are not good neither. Room phone does not work. Pools are for children (only 3 feets of deep at any place) and ..."…"

Reviewed on 28 Oct 2019

Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Villa Gaviota Cayo Coco
Villa Gaviota Cayo Coco
Ciego de Avila, Cayo Santa Maria

Situated in Cayo Santa Maria, this hotel is 3.4 mi (5.5 km) from Cayo Santa Maria Dolphinarium and 5.5 mi (8.9 km) from Playa Las Gaviotas.

Villa Gaviota Cayo Coco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Plan your Cayo Santa Maria holiday with Expedia

  • Our 2020 bundled deals are currently unavailable, but you can now book our 2021 holiday packages deals. Buy your accommodation, flight or car together and get extra savings on your next trip!
  • We have selected for you amazing deals on incredible hotels in Cayo Santa Maria. Have a look simply by using the search bar above.
  • Most hotels come with free cancellation, because we believe that flexibility matters now more than ever!

For more information, visit our COVID-19 information page
Start browsing now!

*Some hotels require you to cancel at least 24-48 hours before check-in.

Frequently asked questions

How much does a Cayo Santa Maria holiday package cost?
From as little as , you can customize your Cayo Santa Maria package the way you want. Simply bundle hotels, flights and rental cars and be rewarded with discounts.
If I'm not able to travel, can I cancel my Cayo Santa Maria holiday package?
It is possible to cancel your Cayo Santa Maria booking if your travel plans have changed. Whether you’ll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Head to our Customer Service Portal for more information.
How do I get a cheap travel package to Cayo Santa Maria?
Our Cayo Santa Maria holiday packages promise plenty of savings for the savvy wanderer. How does as much as 15% sound? That’s what you could save if you combine your hotel, flights and tours into a neat and tidy package. But cheap deals are only the start of your next epic adventure. When you book with Expedia, and you’ll have over 400 air carriers and 321,000 hotel options around the globe to choose from. No matter your budget, there’s a holiday package here just for you.
When is the best time of year to visit Cayo Santa Maria?
If you love the atmosphere of peak season, head to Cayo Santa Maria in . If you’re chasing a calmer vibe, will suit you better. Don’t want to spend a fortune? You might want to avoid , when things like airfares and hotels go up in price. is generally when you’ll score the best deals.
How far in advance should I book my Cayo Santa Maria holiday?
Savvy travellers always book early. Airlines usually release flight tickets around a year ahead of departure, and this is when you can land some rock-bottom prices. Just been told you need to take some holiday time next week? No problem! Expedia are never short of fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Cayo Santa Maria travel package include?
That depends on what kind of getaway you have in the works. Cayo Santa Maria holiday deals can include hotels, flights and car rentals. You can mix and match to find the package that suits you. You can also add on activities and experiences after you’ve booked to get even bigger discounts.
What should I know before booking a Cayo Santa Maria travel package?
So many places to visit, so many things to experience. With a travel package, you can cross more of them off your list. Bundle your flights, rental cars and hotels and get ready to save.
Does Expedia offer Book Now, Pay Later Cayo Santa Maria holiday packages?
Thanks to our partnership with online lender Affirm, holiday makers booking via Expedia can now pay off their journey in small installments that won’t hurt your wallet. Book Now, Pay Later and begin your dream getaway today!
Can I choose my airline with a Cayo Santa Maria Expedia holiday package?
You can. We have more than 550 airline partners all over the world, so choose the carrier that best fits your travel needs.