Find luxury hotels in Cairo, IL

Let Expedia help you arrange your flight to Cairo, IL (CIR-Cairo Regional) airport or Paducah, KY (PAH-Barkley Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay special. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Cairo offers. Cairo has some interesting things to see and do including Mississippi River and Fort Defiance State Park, so you might want to take in the local sights during your visit.

Planning for the weather is an important factor for making your trip to Cairo a success, especially when you’re splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.

Enjoy all that Cairo has to offer and visit Mississippi River, Fort Defiance State Park and Columbus-Belmont State Park. If you have spare time during your trip, you might want to make a stop at Ballard Wildlife Management Area and Mound City National Cemetery.