Barrio Sur Holidays from £526

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Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
£526
per person
22 Dec - 26 Dec
found 9 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
£795
per person
22 Dec - 26 Dec
found 9 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
£631
per person
22 Dec - 26 Dec
found 9 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)
loved my family suite !!! very spacious and cute ! awesome views… the pool was such a vibe even on the days it did rain the bar was still open. great location in the city

Reviewed on 27 Sept 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
£627
per person
22 Dec - 26 Dec
found 9 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9.6/10 Exceptional! (438 reviews)
Enjoyed our stay

Reviewed on 27 Sept 2026

Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
£957
per person
13 Nov - 20 Nov
found 1 day ago
Return direct flight included
London (LHR) to Panama City (PTY)
8.6/10 Excellent! (1,708 reviews)

Where to stay in Barrio Sur

Find the best Barrio Sur areas and neighborhoods for the activities you enjoy most. Learn more about Barrio Sur
A statue of a historical figure pointing upwards with a bird in hand, set against a backdrop of a clear blue sky with scattered clouds.

Barrio Norte

1 out of top 10 points of interest in this area

If you're spending some time in Barrio Norte, Monument to Christopher Columbus and Limon Bay are top sights worth seeing.

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A canal with a lock system, a large cargo ship, and a white building with "PANAMA CANAL" written on it.

Cristobal

Travellers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area.

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Coco Solo

If you're spending some time in Coco Solo, Colon Free Zone and Limon Bay are top sights worth seeing.

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Gatun

Gatun is well liked for its museums and monuments. If you're hoping to see more of the larger area, Canal Expansion Observation Center and Gatún Dam are some interesting sights nearby to check out.

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Top hotels in Barrio Sur

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Paseo Gorgas, Calle 13 Colon Colon
Fully refundableReserve now, pay when you stay
£96
11 Oct - 12 Oct
includes taxes & fees
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Hotel Andros

Hotel Andros

Ave. Herrera, entre Calles 9 y 10 Colon Colon
Fully refundableReserve now, pay when you stay
£37
2 Oct - 3 Oct
includes taxes & fees
8/10 Very good! (175 reviews)
"simpre Bueno"

Reviewed on 25 Sept 2026

Hotel Andros
Hotel Sotelo

Hotel Sotelo

Calle 11, Ave. Amador Colon Panama
£26
29 Sept - 30 Sept
includes taxes & fees
Hotel Sotelo
See all 55 properties in Barrio Sur
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Family Friendly Holidays
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Golf Holidays
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Luxury Holidays
gay friendly holidays
LGBTQ+ Holidays
LGBTQ+ Holidays
Romantic Holidays
Romantic Holidays
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Ski Holidays
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Pet Friendly Holidays
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Where to go when
Where to go when

Stay near popular Barrio Sur attractions

Colon 2000

7.6/10 (88 reviews)
During your visit to Colon, you can do some window-shopping at Colon 2000. Stroll along this relaxing area's lakeside or simply enjoy its restaurants.
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Colon Free Zone

7.8/10 (127 reviews)
During your trip to Colon, you can do some window-shopping at Colon Free Zone.
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Fantastic Casino | Colón 2000

Why not try your luck with a visit to Fantastic Casino | Colón 2000 during your time in Colon?
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Fantastic Casino Colon Calle 13

Why not roll the dice with a visit to Fantastic Casino Colon Calle 13 during your travels in Colon?
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Crown Casino

Why not try your luck with a visit to Crown Casino during your time in Colon?
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Colón Art and Culture Center

Enjoy an outing to Colón Art and Culture Center during your stay in Colon.
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Things to do

Ocean to Ocean Panama Canal and Jungle Tour

Ocean to Ocean Combo: Canal Boat Safari, Agua Clara & Gatun Locks

£64
per adult
94% of travellers recommend
Ocean to Ocean Combo: Canal Boat Safari, Agua Clara & Gatun Locks
Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge

Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge

£37
per adult
Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge
Colon City tour: Exploring Caribbean roots, food, and culture

Colon City Tour Exploring Caribbean Roots Food and Afro Culture

£78
per adult
Colon City Tour Exploring Caribbean Roots Food and Afro Culture
See all activities in Colon

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.