Title: Barrio Sur Holidays 2026 from £572 | Expedia.co.uk [Hotels in Barrio Sur](https://expedia.co.uk/Barrio-Sur-Hotels.d829297886230487040.Travel-Guide-Hotels)[Flights to Colon](https://expedia.co.uk/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights)[Things to do in Colon](https://expedia.co.uk/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities)[Barrio Sur Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Barrio-Sur.d829297886230487040.Car-Hire-Guide) ![](https://images.trvl-media.com/place/829297886230487040/f369fa93-5766-4cf5-866c-bfa1cf04f904.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Barrio Sur Holidays from £572 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £572 per person 12 Jun - 15 Jun found 23 hours ago Return flight included Kingston (KIN) to Panama City (PTY) 9/10 Wonderful! (5,100 reviews) Overall a good place to stay, excellent and friendly staff, great variety of tasty food, spacious rooms. misses small details such as providing robes, disposable flip-flops, kettles for tea. Reviewed on 27 Mar 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £710 per person 12 Jun - 15 Jun found 23 hours ago Return flight included Kingston (KIN) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Such a beautiful hotel!!! I chose it because of the stair case but was floored when I saw it in person. Gorgeous, peaceful.It was a dream fantasy come to fruition!!! The location perfect. Few feet away from the presidential plaza. There was something happening everyday right outside the hotel all the time. The staff so welcoming, breakfast was delicious. The city the people. I cannot say enough Panama and its people. So welcoming. I will definitely stay there again and longer. It was like staying in a movie. I see why our people move there and why citizens rarely move out this country Reviewed on 20 Mar 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £638 per person 12 Jun - 15 Jun found 23 hours ago Return flight included Kingston (KIN) to Panama City (PTY) 8.4/10 Very Good! (1,448 reviews) Breakfast was great everything was very clean lots of restaurants near by Reviewed on 27 Mar 2026 ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/890b736a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites £815 per person 12 Jun - 15 Jun found 23 hours ago Return direct flight included London (LON) to Panama City (PTY) 9.4/10 Exceptional! (6 reviews) This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again. Reviewed on 16 Mar 2026 ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Las Americas Golden Tower Panama San Francisco £581 per person 12 Jun - 15 Jun found 23 hours ago Return flight included Kingston (KIN) to Panama City (PTY) 9/10 Wonderful! (1,017 reviews) Great hotel , great location Reviewed on 27 Mar 2026 ## Where to stay in Barrio Sur Find the best Barrio Sur areas and neighborhoods for the activities you enjoy most. [Learn more about Barrio Sur](https://expedia.co.uk/Barrio-Sur.dx829297886230487040) ![Cristobal](https://images.trvl-media.com/place/6024083/8bf71600-226a-4a20-b277-bfebc4783659.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Cristobal Travellers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area. [Find hotels in Cristobal](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6024083) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Gatun Gatun is well liked for its museums and monuments. If you're hoping to see more of the larger area, Canal Expansion Observation Center and Gatun Locks are some interesting sights nearby to check out. [Find hotels in Gatun](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6025905) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Coco Solo If you're spending some time in Coco Solo, Colon Free Zone and Limon Bay are top sights worth seeing. [Find hotels in Coco Solo](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248635974899440) ![Barcelona Christopher Columbus monument](https://images.trvl-media.com/place/829297880595460096/89637f4a-c300-40a8-906c-431bcafa7516.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Barrio Norte 1 out of top 10 points of interest in this area If you're spending some time in Barrio Norte, Limon Bay and Monument to Christopher Columbus are top sights worth seeing. [Find hotels in Barrio Norte](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=829297880595460096) ## Top hotels in Barrio Sur ![Radisson Colon 2,000 Hotel & Casino](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Radisson Colon 2,000 Hotel & Casino Paseo Gorgas, Calle 13 Colon Colon Fully refundableReserve now, pay when you stay £90 1 Apr - 2 Apr includes taxes & fees 8.2/10 Very Good! (884 reviews) The the guys Javier and Mariangel by the reception was very helpful and very professional. Thank you for helping me and make my stay nice Reviewed on 27 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F04%2F2026&endDate=02%2F04%2F2026&selected=2147349&PinnedHotelID=2147349&HadPinnedHotel=true®ionId=829297886230487040) ![Hotel Sotelo](https://images.trvl-media.com/lodging/24000000/23360000/23358200/23358184/5961aa1e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Sotelo Calle 11, Ave. Amador Colon Panama Fully refundableReserve now, pay when you stay £26 28 Mar - 29 Mar includes taxes & fees [](https://expedia.co.uk/Hotel-Search?startDate=28%2F03%2F2026&endDate=29%2F03%2F2026&selected=23358184&PinnedHotelID=23358184&HadPinnedHotel=true®ionId=829297886230487040) ![Hotel Andros](https://images.trvl-media.com/lodging/12000000/11640000/11631800/11631712/b2e8e395_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Andros Ave. Herrera, entre Calles 9 y 10 Colon Colon 8/10 Very Good! (160 reviews) All great Reviewed on 31 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&selected=11631712&PinnedHotelID=11631712&HadPinnedHotel=true®ionId=829297886230487040) [](https://expedia.co.uk/Hotel-Search?startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&selected=11631712&PinnedHotelID=11631712&HadPinnedHotel=true®ionId=829297886230487040) [See all 45 properties in Barrio Sur](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=28%2F03%2F2026&endDate=29%2F03%2F2026®ionId=829297886230487040) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit #### Colon Free Zone During your trip to Colon, you can do some window-shopping at Colon Free Zone. [](https://expedia.co.uk/Colon-Free-Zone-Barrio-Sur.d6078503.Attraction) ### Things to do ![Ocean to Ocean Panama Canal and Jungle Tour](https://mediaim.expedia.com/localexpert/1017208/c457e1f7-f5e8-43ef-82cc-1459d2c10f4d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ocean to Ocean Combo: Canal Boat Ride, Locks, Fort San Lorenzo £100 per adult **94%** of travellers recommend [](https://expedia.co.uk/things-to-do/ocean-to-ocean-combo-canal-boat-ride.a1017208.activity-details) ![Shopping in the Biggest duty free zone of Las Americas in a day ](https://mediaim.expedia.com/localexpert/50762780/ca8b2ca8-bfe5-4612-89f9-487f74e7deec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Shopping in the Biggest duty free zone of Las Americas in a day £37 per adult [](https://expedia.co.uk/things-to-do/shopping-in-the-biggest-duty-free-zone-of-las-americas-in-a-day.a50762780.activity-details) ![Transfers to the Colon Cruise Port](https://mediaim.expedia.com/localexpert/49288946/b8036a78-4dd2-41c2-b7fd-a52e92bf155d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panama Cruise Package: Transfer, Hotel and City Tour £227 per adult [](https://expedia.co.uk/things-to-do/panama-cruise-package-transfer.a49288946.activity-details) [See all activities in Colon](https://expedia.co.uk/things-to-do/search?rid=829297886230487040) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.