Antofagasta Region Holidays
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Your Antofagasta Region Holiday
Leave the travel planning up to us with an Antofagasta Region holiday package. With everything arranged before you jet off, all you need to do is relax and enjoy this destination's culture and charm. Your trip to Antofagasta Region wouldn't be complete without exploring some of its most well-known cities, starting with San Pedro de Atacama. A couple of the top attractions here include Piedra del Coyote Overlook and San Pedro Church. Antofagasta is another favourite city with Antofagasta Region travellers. Visitors to this exciting city enjoy Antofagasta Fish Market and Central Market. From the moment you book your Antofagasta Region holiday to when you get back home, Expedia has you covered every step of the way.
Top destinations in Antofagasta Region
Antofagasta (region)
Taste fresh seafood from the Pacific Coast and explore the salt flats and arid lava flows of the highlands plateau in this large region in Chile’s north.
With vast arid landscapes that plunge into the cliff-edged Pacific Ocean, Antofagasta is the second-largest region in Chile and is crowned by the city of the same name. The dramatic region is characterized by the altiplano highland plateaus, but is fringed to the west by a string of charming seaside villages and fishing wharves.
Explore the city of Antofagasta to relax on the waterfront and sample fresh local seafood, or check out inland Calama to experience the desert landscapes that transform into the unparalleled Atacama.
Begin your travels in this vast region with a visit to the city of Antofagasta. Stroll along the city’s charming waterfront and watch fishing boats coming and going from the wharf. At the fishing harbour, you can watch sea lions, pelicans and seabirds being fed fish from the day’s catch. Visit a local fishmonger or a seafood restaurant to try some of the catch for yourself.
Visit geological formations at La Portada Natural Monument, which is an impressive coastal cliff comprised of volcanic rocks and fossils. Explore the vast beaches of Playa Grande when you check out the nearby town of Mejillones.
Explore inland to the town of Calama to reach the gateway to Antofagasta’s remote wilderness. You can visit a vast open-cut mine, Chuquicamata, in this town. If you are up to the challenge, rent a four-wheel drive and explore the moonscape scenery of the surrounding salt flats. You can also reach Chiu-Chiu and its ruins, churches and lagoons.
Continue northeast to reach the eerie plumes of the Geyser of Tatio. Calama is an interesting stopover for travellers heading toward San Pedro de Atacama and the Atacama Desert.
Reach Antofagasta via the airports in Calama or the city of Antofagasta. There are several buses that connect the towns and smaller communities in Antofagasta and its neighbour, Atacama. In the region’s towns, you can hire taxis, catch local buses or explore on foot.
With its fascinating desert landscapes and scenic coastal towns, Antofagasta is an ideal destination on your adventures in Northern Chile.
Antofagasta Region Essential Information
Language | Spanish |
|---|---|
Currency | Chilean pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Cerro Moreno Intl. Airport (ANF) |
Population | 309,800 |
Top Sights | Valley of the Moon, Arco Iris Valley and Piedra del Coyote Overlook |
Top hotels in Antofagasta Region
Diego de Almagro San Pedro de Atacama
"Staff very helpful and friendly, although no English. Happy to converse using translation tools. Swimming pool was closed due to it being winter, which I didn’t reslise when I booked. A couple of times there was no water, no electricity and no wifi, but staff worked to resolve the issue. Breakfast ..."
Reviewed on 18 Jul 2026
Geotel Calama
"Great stay, lovely breakfast. Nice and quiet and easy walk to town square. Highly recommend"
Reviewed on 16 Sept 2026
Hotel La Casa de Don Tomas
"We arrived for our reservation and were moved to their Refugio down the street. They had parking and were very kind and accommodating. The breakfast, coffee and tea was excellent and much appreciated. Rooms were clean and well maintained; everything looked new. The view from our room was ..."
Reviewed on 1 Oct 2026
Frequently asked questions
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- Pay monthly holidays: Klarna offers manageable monthly payment plans that fit all budgets, so you can book that well-earned holiday sooner.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your holiday over multiple transactions.
- Low deposit holidays: Hitting the "book now" button is easier with this plan. Simply put down a small deposit on your escape and then start packing your bags.
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Stay near popular Antofagasta Region attractions
Valley of the Moon
Pukara de Quitor Archaeological Site
Plaza de San Pedro de Atacama
Cerro Paranal Observatory
San Pedro Church
Mall Plaza Calama
Valle Da La Muerte
Piedra del Coyote Overlook
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
