Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santorini Island 5 Star Hotels

See all 942 Hotels in Santorini Island
Lilium Villas

Lilium Villas

Fira Town, Santorini
5.0 out of 5.0
4.8 out of 5 (267 reviews)
Beautiful View!Found the hotel to be kept very clean, the view was spectacular! Nice breakfast buffet is included and WiFi for entire stay! The people were friendly and very helpful. Shuttle to Fira runs several times a day and I to the evening. Highly recommend!
  7 Nov 2017
Andronis Boutique Hotel

Andronis Boutique Hotel

Oia, Santorini
5.0 out of 5.0
4.8 out of 5 (105 reviews)
THE BESTNo words to explain it, beyond of any expectavives
  25 Oct 2017
Santorini Princess Luxury Spa Hotel

Santorini Princess Luxury Spa Hotel

Imerovigli, Santorini
5.0 out of 5.0
4.8 out of 5 (446 reviews)
This was one of the best hotel experiences...ever!I travel extensively for work and this was one of the best overall experiences. The staff is incredibly hospitable and the service was amazing. The food was our faborite of the trip. I would highly recommend this resort and would stay again.
  6 Nov 2017
De Sol Spa Hotel

De Sol Spa Hotel

Fira, Santorini
5.0 out of 5.0
4.6 out of 5 (55 reviews)
Very comfortable!The hotel is beautifully located and very comfortable. Staff is friendly and attentive to all our needs.
  14 Jan 2018

£81

£81
Katikies Hotel

Katikies Hotel

Oia, Santorini
5.0 out of 5.0
4.8 out of 5 (131 reviews)
Great location, beautiful hotelVery nice and well kept hotel, with great sunset views. Very friendly staff, well located with very easy access in beautiful OIA in Santorini.
  1 Nov 2017
Astro Palace

Astro Palace

Eikostis Pemptis Martiou, Santorini
5.0 out of 5.0
4.5 out of 5 (383 reviews)
Good experience Very good experience and would do it again. Definitely good to go there better between june to August
  27 Oct 2017
Dreams Luxury Suites

Dreams Luxury Suites

Imerovigli, Santorini
5.0 out of 5.0
4.7 out of 5 (43 reviews)
Beautiful place to stayWe had the best stay at dreams. The staff are a 10/10, room facilities 10/10, value for money 10/10, location 10/10. We were lucky enough o stay at one of the 6 boutique rooms, it was the best holiday ever and the staff at Dreams made our stay even better, always recommending places for us to go ...
  25 Oct 2017
Alta Vista Suites

Alta Vista Suites

Imerovigli, Santorini
5.0 out of 5.0
4.7 out of 5 (94 reviews)
Great place to stay.Fantastic suites with views over the water and Fira. A short walk to restaurants and Tavernas. Vasilin the manager arranged for airport transport and met us and carried our bags to our wonderful room. Great staff, delicious breakfasts eaten overlooking the sea.
  6 Jan 2018

£98

£98
Andronis Luxury Suites

Andronis Luxury Suites

Oia, Santorini
5.0 out of 5.0
4.8 out of 5 (106 reviews)
First; the view was amazing. Staff was super helpful, and nice. Room was perfect, when we got there our hot tub was a little cold for us but they cranked the heat up ASAP. There is some pretty good stairs to get to any room there but the staff handles all your luggage (thankful for that!). All in ...
  31 Oct 2017
Volcano View Hotel & Villas

Volcano View Hotel & Villas

Fira, Santorini
5.0 out of 5.0
4.5 out of 5 (315 reviews)
Perfect break away We highly recommend this hotel to all those that are enquiring. The airport transfer was easy and the location of the hotel form the airport made it super quick yet not too close. We received the complimentary buffet breakfast each morning where we were greeted by welcoming staff and a delicious ...
  1 Nov 2017
Map

Pocket Guide: 5 Star Hotels in Santorini Island

Search for hotels in Santorini Island on Expedia.co.uk. You can easily find your hotels in Santorini Island using one of the methods below:

  • View our selection of featured hotels in Santorini Island
  • Use the map to find hotels in the Santorini Island neighborhood you prefer
  • Use the filters to see hotels in a specific area of Santorini Island, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Santorini Island
  • Enter your travel dates to view the best deals on hotels in Santorini Island - while they last

Recently booked Santorini Island hotels

Grand View
3.5 out of 5.0
Last booking: 1 hour ago
Agnadema Apartments
4.0 out of 5.0
Last booking: 1 hour ago
Elite Luxury Suites
5.0 out of 5.0
Last booking: 3 hours ago
Aspa Villas
4.0 out of 5.0
Last booking: 5 hours ago
Loizos Apartments
4.0 out of 5.0
Last booking: 7 hours ago
Oia Mare Villas
4.5 out of 5.0
Last booking: 7 hours ago
Dream Island Hotel
3.5 out of 5.0
Last booking: 7 hours ago
Aethrio
3.5 out of 5.0
Last booking: 8 hours ago
1864 The Sea Captain's House
4.0 out of 5.0
Last booking: 9 hours ago