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Featured Texas Medical Center 4 Star Hotels

See all 589 Hotels in Texas Medical Center
Sheraton North Houston at George Bush Intercontinental

Sheraton North Houston at George Bush Intercontinental

15700 John F Kennedy Blvd, Houston
4.0 out of 5.0
4.2 out of 5 (1,504 reviews)
Would stay here againGave it 4 out of 5. The staff were wonderful. They had a pleasant demeanor and were very helpful in answering our questions. Checkin was easy and took less than 5 minutes. They also provided us with extra amenities (razors, gels, etc). The room was clean, smelled good, was the perfect temperature, ...
  21 Jan 2018

£66

£66
Hotel Derek Houston Galleria

Hotel Derek Houston Galleria

2525 West Loop S, Houston
4.5 out of 5.0
4.0 out of 5 (2,883 reviews)
Had a romantic evening for my girlfriend and everything was up to par. Not really used to hotels like these, so we enjoyed it to the fullest.
  16 Jan 2018

£75

£75
Club Quarters Hotel in Houston

Club Quarters Hotel in Houston

720 Fannin Street, Houston
4.5 out of 5.0
4.0 out of 5 (4,964 reviews)
Very dissapointed with YOU Expedia!I got to the hotel and there was no reservation, you have charged me and didn’t send the reservation to the Hotel. The people from the hotel tracked the reservation on line and gave an upgrade -after almost 20 minutes from arrival. Very happy with the hotel staff but I think it was very unprofessional ...
  16 Jan 2018

£62

£62
Royal Sonesta Houston Galleria

Royal Sonesta Houston Galleria

2222 West Loop South, Houston
4.5 out of 5.0
4.4 out of 5 (1,607 reviews)
Very nice hotel with convenient location, close to the Gallery Mall and freeway.
  19 Jan 2018

£101

£101
Wyndham Houston - Medical Center Hotel and Suites

Wyndham Houston - Medical Center Hotel and Suites

6800 Main Street, Houston
4.0 out of 5.0
3.9 out of 5 (1,433 reviews)
Nice HotelExcellent cleanliness. Nice and safe location Just a few streets down from a CVS which is super convenient
  22 Jan 2018

£71

£71
Omni Houston Hotel Westside

Omni Houston Hotel Westside

13210 Katy Fwy, Houston
4.5 out of 5.0
4.2 out of 5 (2,228 reviews)
Very nice stay!Booked the Omni last minute, then night we intended to stay. I saw the reviews and was a little worried, but it was a good rate and the last Omni we stayed in was a good experience. Valet were very pleasant, and check-in was quick and friendly. Our room was very clean, quite large and nicely appointed ...
  12 Jan 2018

£58

£58
Wyndham Houston West Energy Corridor

Wyndham Houston West Energy Corridor

14703 Park Row, Houston
4.0 out of 5.0
3.9 out of 5 (1,168 reviews)
Nice older hotel, I had stayed in it years ago and it's been kept up nicely.
  10 Jan 2018

£86

£86
Hilton Americas - Houston

Hilton Americas - Houston

1600 Lamar Street, Houston
4.5 out of 5.0
4.6 out of 5 (3,119 reviews)
Five star. Lots of class.And I found a hotel to match :-) Clean rooms. Good service. Great food. Nice New Years.
  15 Jan 2018

£117

£117
Hilton Houston Galleria Area

Hilton Houston Galleria Area

6780 Southwest Freeway, Houston
4.5 out of 5.0
4.0 out of 5 (853 reviews)
Houston hotel near GalleriaGreat hotel right off the highway, about 20 minutes from the medical district
  19 Jan 2018

£73

£73
Aloft Houston by the Galleria

Aloft Houston by the Galleria

5415 Westheimer Road, Houston
4.0 out of 5.0
4.1 out of 5 (2,400 reviews)
Not quite as good as other Aloft HotelsThe main issues with my stay were: 1) Elevators were slow and limited in number; 2) the hallway outside my room has a cleaning agent/dank smell and 3) NO HOT WATER the morning of my departure. Luckily the water wasn't frigid.
  21 Jan 2018

£51

£51
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4 stars in Texas Medical Center

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Recently booked Texas Medical Center hotels

Americas Best Value Inn-Medical Center Downtown
2.0 out of 5.0
Last booking: 2 hours ago
SureStay Plus Hotel by Best Western Houston Medical Center
3.0 out of 5.0
Last booking: 2 hours ago
Quality Inn & Suites NRG Park - Medical Center
2.5 out of 5.0
Last booking: 3 hours ago
Hotel Zaza Houston Museum District
4.0 out of 5.0
Last booking: 3 hours ago
Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd
2.5 out of 5.0
Last booking: 3 hours ago
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
3.0 out of 5.0
Last booking: 4 hours ago
Hotel Ylem
3.5 out of 5.0
Last booking: 6 hours ago
Wyndham Houston - Medical Center Hotel and Suites
4.0 out of 5.0
Last booking: 6 hours ago
Houston Marriott Medical Center/Museum District
4.5 out of 5.0
Last booking: 6 hours ago