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Featured Tenderloin 4 Star Hotels

See all 659 Hotels in Tenderloin
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,379 reviews)
Great hotel! Very close to everything, can walk to fishermans wharf shopping and dining. They also offer free bike rentals! You can ride anywhere that your athletic ability allows! We rode to the Golden Gate Bridge and across it. And even went to china town and golden gate park. Tough rides but worth ...
  19 Oct 2017

£119

£119
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,635 reviews)
valueWell the hotel is in the Tenderloin so ya it's a little rough, but be smart about it. It is just at the edge of the Tenderloin. Make sure to turn left when you leave the hotel or left onto O'farell and it's fine Great places nearby like Liho Liho Yacht Club! Waited at the bar for a spot was insanely ...
  16 Oct 2017

£117

£117
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,837 reviews)
Beautiful historic hotel in the heart of San FrancIt was a wonderful experience staying at the St. Francis. WE really loved learning about all the history that occurred there, and being in an area that was so convenient to restaurants and shopping. We especially enjoyed the wine tasting with Chateau Montelena since that is one of our favorite wineries. ...
  18 Oct 2017

£164

£164
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,779 reviews)
Good location near Union Square, restaurants, shopping. Comfortable clean Hotel
  19 Oct 2017

£142

£142
Hilton San Francisco Downtown/Financial District

Hilton San Francisco Downtown/Financial District

750 Kearny St, San Francisco
4.0 out of 5.0
4.0 out of 5 (1,195 reviews)
Last minute gatewaylast minute change of plans, hotel was convenient in the area we wanted to be. Great front desk people, room service fast, and outstanding. Extremely friendly..........would stay there again...
  17 Oct 2017

£117

£117
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,659 reviews)
First visit to San FranciscoGreat place. Close to everything. Arrived on Saturday morning and but room wasn't going to be ready till 4pm. They did check our luggage and when we got back took it to our room. Our room was next to the elevators which made it a bit noisy at times and we could hear the elevators all night going ...
  18 Oct 2017

£154

£154
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,387 reviews)
Very nice hotel. Great location too. Check-in was very quick. Front desk person was able to find a nice room facing Union Square for us even though we arrived in the morning. Staff was helpful and friendly at all times. Room service was excellent too.
  13 Oct 2017

£159

£159
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,991 reviews)
Very convenient location!!We stayed in tower 3 so old,and smells like the room is wet !
  18 Oct 2017

£156

£156
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,278 reviews)
Close to airportSpent one night, layover before Hawaii went into San Francisco use Uber will save $$. Hotel staff very friendly and helpful, clean and Air port shuttle 24 hours
  18 Oct 2017

£137

£137
Sheraton Fisherman's Wharf Hotel

Sheraton Fisherman's Wharf Hotel

2500 Mason St, San Francisco
4.0 out of 5.0
3.9 out of 5 (2,454 reviews)
Great Hotel close to all sightseeing highlights.Fantastic stay, loved sitting by fire pits with a glass of wine after a long day sightseeing.
  19 Oct 2017

£144

£144
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Pocket Guide: 4 Star Hotels in Tenderloin

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Recently booked Tenderloin hotels

Serrano Hotel
4.0 out of 5.0
Last booking: 1 hour ago
Warwick San Francisco
4.0 out of 5.0
Last booking: 2 hours ago
The Marker San Francisco, a Joie de Vivre Hotel
4.0 out of 5.0
Last booking: 2 hours ago
Axiom Hotel San Francisco
4.0 out of 5.0
Last booking: 4 hours ago
Parc 55 San Francisco - A Hilton Hotel
4.0 out of 5.0
Last booking: 4 hours ago