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This region of forests and thermal spas takes its name from the River Chiana, a well-traversed waterway between Arezzo and Siena provinces. The once-malarial marshes have long been drained, leaving small lakes behind. Chiusi, an ancient Etruscan town, dominates the valley headwaters, while Montepulciano surveys the broad floodplain from its hilltop vantage point. Chianciano and San Casciano dei Bagni have therapeutic hot springs.